Evidence map›Paper›PMID 33530695›Full record

ArticleAmerican journal of Alzheimer's disease and other dementias

Examining Depression Symptoms With/Without Coexisting Anxiety Symptoms in Community-Dwelling Persons With Dementia.

Alexandra A Sibley, Srijana Shrestha, Martha Lipovac-Dew, Mark E Kunik

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in American journal of Alzheimer's disease and other dementias. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02380703 (Aggression Prevention Training for Caregivers of Persons With Dementia), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02380703 nacompletednot on this map

Aggression Prevention Training for Caregivers of Persons With Dementia (APT)

TypeinterventionalSponsorBaylor College of MedicineRan2015 to 2018Enrolled239ConditionsDementia, Pain, Alzheimer's Disease, AggressionArmsAggression Prevention Training (APT), Enhanced Usual Primary Care (EU-PC)
3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Alexandra A SibleyDepartment of Psychiatry and Human Behavior, University of Mississippi Medical Center, Jackson, MS, USA.ORCID 0000-0001-6714-0508
Srijana ShresthaPsychology Department, Wheaton College, Norton, MA, USA.
Martha Lipovac-DewMenninger Department of Psychiatry and Behavioral Sciences, Baylor College of Medicine, Houston, TX, USA.
Mark E KunikMenninger Department of Psychiatry and Behavioral Sciences, Baylor College of Medicine, Houston, TX, USA.ORCID 0000-0002-7349-5521
Baylor College of Medicine · USJackson Memorial Hospital · USMichael E. DeBakey VA Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Depression and anxiety are common in persons with dementia (PWD) and associated with poor outcomes. We explored frequency, pharmacologic management and mental health service use in PWD and depression symptoms with/without coexisting anxiety symptoms. The sample comprised 160 community-dwelling PWD in a trial to prevent development of aggression. Baseline data on depression and anxiety symptoms, psychotropic medications and mental health service use were examined. Regarding participants, 65 (41%) lacked clinically significant depression or anxiety symptoms, 45 (28%) had depression symptoms, 43 (27%) had depression and anxiety symptoms, and 7 (4%) had anxiety symptoms. Comorbid anxiety was associated with more severe depression symptoms. One third with depression symptoms and one half with depression and anxiety symptoms were taking an antidepressant. Mental health service use was very low, regardless of depression symptom severity or coexisting anxiety. Research needs to evaluate therapies for depressed PWD, but treatment of those with comorbid anxiety and depression is more urgent. Clinical Trial Registration for Parent Trial: ClinicalTrials.gov (NCT02380703).

Indexed as

AnxietyDementiaDepressionDepressive DisorderClinical Trials as TopicHumansIndependent LivingMental Health Servicesanxietydementiadepression; pharmacologic therapymental health

Identifiers

PMID33530695
PMCPMC10624070
OpenAlexW3126712252

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.