Evidence map›Paper›PMID 33530679›Full record

ArticleAnesthesia and pain medicine2021

Capillary leak syndrome and disseminated intravascular coagulation after kidney transplantation in a patient with hereditary angioedema - A case report.

Jeong Wook Park, Jinyoung Seo, Sang Hun Kim, Ki Tae Jung

Open access · goldAbstract readCase Reports
In one paragraph

Article in Anesthesia and pain medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Jeong Wook ParkDepartment of Anesthesiology and Pain Medicine, Chosun University Hospital, Gwangju, Korea.
Jinyoung SeoDepartment of Anesthesiology and Pain Medicine, Chosun University Hospital, Gwangju, Korea.
Sang Hun KimDepartment of Anesthesiology and Pain Medicine, Chosun University Hospital, Gwangju, Korea.
Ki Tae JungDepartment of Anesthesiology and Pain Medicine, Chosun University Hospital, Gwangju, Korea.
Chosun University · KRChosun University Hospital · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHereditary angioedema (HAE) is a rare disease caused by the deficiency of C1 esterase inhibitor. HAE has a risk of life-threatening complications such as capillary leak syndrome (CLS) and disseminated intravascular coagulation (DIC). CASE: A 42-year-old male patient with HAE presented for deceased-donor kidney transplantation. Prophylactic fresh frozen plasma (FFP) was given before surgery because of the risk of edema development. With careful management during anesthesia, there were no problems during surgery. However, generalized edema, hypotension, hypoalbuminemia, massive drainage of serosanguineous fluids from the intraabdominal space, and DIC occurred on the day after surgery. CLS was suspected and sustained hypotension with generalized edema became worse despite treatment with albumin, danazol, FFP, and vasoactive drugs. The patient's condition worsened despite intensive care and he died due to shock.

conclusionsThe anesthesiologist should prepare for the critical complications of HAE and prepare the appropriate treatment options.

Indexed as

Capillary leak syndromeComplement C1 inhibitor proteinComplement C1sDisseminated intravascular coagulationHereditary angioedemaKidney transplantation

Identifiers

PMID33530679
PMCPMC7861902
OpenAlexW3123341979

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.