Evidence map›Paper›PMID 33530637›Full record

ArticleGenes2021

The Axenfeld-Rieger Syndrome Gene

Paul W Chrystal, Curtis R French, Francesca Jean, Serhiy Havrylov, Suey van Baarle, Ann-Marie Peturson, Pengfei Xu, J Gage Crump, David B Pilgrim, Ordan J Lehmann and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Genes, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Zebrafish Congenital Heart Disease Models: Opportunities and Challenges.International journal of molecular sciences · 2024
    Review
  3. Mutation ofGenes · 2022
    Article
  4. Article
  5. Mechanistic Insights into Axenfeld-Rieger Syndrome from ZebrafishInternational journal of molecular sciences · 2021
    Review
  6. Getting to the Heart of Left-Right Asymmetry: Contributions from the Zebrafish Model.Journal of cardiovascular development and disease · 2021
    Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Paul W ChrystalDepartment of Medical Genetics, University of Alberta, Edmonton, AB T6G 2H7, Canada.ORCID 0000-0002-5371-1178
Curtis R FrenchDepartment of Medical Genetics, University of Alberta, Edmonton, AB T6G 2H7, Canada.
Francesca JeanDepartment of Biological Sciences, University of Alberta, Edmonton, AB T6G 2E9, Canada.
Serhiy HavrylovDepartment of Medical Genetics, University of Alberta, Edmonton, AB T6G 2H7, Canada.
Suey van BaarleDepartment of Medical Genetics, University of Alberta, Edmonton, AB T6G 2H7, Canada.
Ann-Marie PetursonDepartment of Biological Sciences, University of Alberta, Edmonton, AB T6G 2E9, Canada.
Pengfei XuDepartment of Stem Cell Biology and Regenerative Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA.
J Gage CrumpDepartment of Stem Cell Biology and Regenerative Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA.
David B PilgrimDepartment of Biological Sciences, University of Alberta, Edmonton, AB T6G 2E9, Canada.
Ordan J LehmannDepartment of Medical Genetics, University of Alberta, Edmonton, AB T6G 2H7, Canada.ORCID 0000-0003-4141-7411
Andrew J WaskiewiczDepartment of Biological Sciences, University of Alberta, Edmonton, AB T6G 2E9, Canada.ORCID 0000-0002-5306-0643
University of Alberta · CAUniversity of Southern California · USMemorial University of Newfoundland · CA

Funding

Progenitor Regulation in Craniofacial Development and RegenerationR35DE027550 · NIDCR · UNIVERSITY OF SOUTHERN CALIFORNIA · PI CRUMP, GAGE D · 2017 to 2024
$8.0M
CIHRNIDCR NIH HHS R35 DE027550
6 · The paper itself

Abstract

Precise spatiotemporal expression of the

Indexed as

Genetic Association StudiesGenetic Predisposition to DiseasePhenotypeAllelesAnimalsAnterior Eye SegmentComputational BiologyDisease Models, AnimalEye AbnormalitiesEye Diseases, HereditaryForkhead Transcription FactorsGene Expression ProfilingGenotypeHumansMesodermMutationForkhead Transcription FactorsFOXC1 protein, humanAxenfeld–Rieger syndromeFOXC1left–right patterningLEFTYzebrafish

Identifiers

PMID33530637
PMCPMC7912076
OpenAlexW3125202435

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.