Evidence map›Paper›PMID 33530472›Full record

ArticleInternational journal of molecular sciences2021

Loss of

Pavla Brachova, Nehemiah S Alvarez, Lane K Christenson

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Pavla BrachovaDepartment of Molecular and Integrative Physiology, University of Kansas Medical Center, Kansas City, KS 661601, USA.ORCID 0000-0002-9014-132X
Nehemiah S AlvarezDepartment of Molecular and Integrative Physiology, University of Kansas Medical Center, Kansas City, KS 661601, USA.
Lane K ChristensonDepartment of Molecular and Integrative Physiology, University of Kansas Medical Center, Kansas City, KS 661601, USA.ORCID 0000-0003-3846-5674
University of Kansas Medical Center · US

Funding

Mitochondrial RNA defense pathways in the oocyteR01HD094545 · NICHD · UNIVERSITY OF KANSAS MEDICAL CENTER · PI CHRISTENSON, LANE K. · 2018 to 2022
$1.8M
A-to-I RNA modifications in mouse oocytesK99HD099269 · NICHD · UNIVERSITY OF KANSAS MEDICAL CENTER · PI BRACHOVA, PAVLA · 2019 to 2020
$235k
NICHD NIH HHS K99 HD099269NICHD NIH HHS R01 HD094545
6 · The paper itself

Abstract

Mammalian oocytes must degrade maternal transcripts through a process called translational mRNA decay, in which maternal mRNA undergoes translational activation, followed by deadenylation and mRNA decay. Once a transcript is translationally activated, it becomes deadenylated by the CCR4-NOT complex. Knockout of CCR4-NOT Transcription Complex Subunit 6 Like (

Indexed as

AnimalsEmbryonic DevelopmentGene Expression RegulationInosine NucleotidesMiceMice, KnockoutOocytesOogenesisOpen Reading FramesRibonucleasesRibosomesRNARNA, MessengerRNA Processing, Post-TranscriptionalRNA StabilityCnot6l protein, mouseInosine NucleotidesRibonucleasesRNARNA, MessengerADARCCR4-NOTGV-to-MII transitioninosine RNA modificationsoocytepolysomeRNA decaytranslation

Identifiers

PMID33530472
PMCPMC7865253
OpenAlexW3125502057

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.