SynthesisMedicine2021
The impact of coronavirus disease 2019 (COVID-19) on liver injury in China: A systematic review and meta-analysis.
Synthesis in Medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Risk factors and prognosis for COVID-19-induced acute kidney injury: a meta-analysis.BMJ open · 2020Pooled it
- New Onset of Acute and Chronic Hepatic Diseases Post-COVID-19 Infection: A Systematic Review.Biomedicines · 2024Review
- The impact of COVID-19 on the clinical course and outcome of patients with cirrhosis: An observational study.Health science reports · 2024Article
- COVID-19 associated liver injury: An updated review on the mechanisms and management of risk groups.Liver research (Beijing, China) · 2023Review
- The Impact of the COVID-19 Pandemic on Outcomes in Acute Pancreatitis: A Propensity Score Matched Study Comparing before and during the Pandemic.Diagnostics (Basel, Switzerland) · 2023Article
- A Surgical Perspective of Gastrointestinal Manifestations and Complications of COVID-19 Infection.Gastroenterology clinics of North America · 2023Review
- Commentary on COVID-19-induced liver injury in various age and risk groups.World journal of virology · 2023Review
- Significance of digestive symptoms after COVID-19 vaccination: A retrospective single-center study.The American journal of emergency medicine · 2022Article
- [Analysis of differences and influencing factors of liver injury associated with different strains of 2019-nCoV infection].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2022Article
- Article
- Laboratory Findings in Different Disease Status of COVID-19 Admitted Patients at Dilla University Referral Hospital Treatment Center, South Ethiopia.Infection and drug resistance · 2022Article
- Pregnancy and COVID-19 - liver damage.Medicine and pharmacy reports · 2021Article
- Does the COVID-19 Pandemic Affect Morbidity and Mortality Rates of Emergency General Surgery? A Retrospective Study from a Single-Center Tertiary Greek Hospital.Medicina (Kaunas, Lithuania) · 2021Article
- Evaluation of liver function in symptomatic COVID-19 patients.Journal of family medicine and primary care · 2021Article
- Article
- The Relationship of Liver and Pancreas Density With Chest Computed Tomography Score Progression and Laboratory Findings in Patients With COVID-19.Journal of computer assisted tomographyArticle
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionThe evidence for the incidence and severity of liver injury in Chinese patients with coronavirus disease 2019 (COVID-19) is still controversial. The purpose of this study was to summarize the incidence of liver injury and the differences between liver injury markers among different patients with COVID-19 in China.
methodsComputer searches of PubMed, Embase, China National Knowledge Infrastructure (CNKI) and medRxiv were used to obtain reports on the incidence and markers of liver injury in Chinese patients with COVID-19, from January 1, 2020 to April 10, 2020. (No. CRD42020181350).
resultsA total of 57 reports from China were included, including 9889 confirmed cases of COVID-19 infection. The results of the meta-analysis showed that among the patients with early COVID-19 infection in China, the incidence of liver injury events was 24.7% (95% CI, 23.4%-26.4%). Liver injury in severe patients was more common than that in non-severe patients, with a risk ratio of 2.07 (95% CI, 1.77-2.43). Quantitative analysis showed that the severe the coronavirus infection, the higher the level of alanine aminotransferase (ALT), aspertate aminotransferase (AST), total bilirubin (TB), alkaline phosphatase (ALP), γ-glutamyl transpeptidase (GGT), and the lower the level of albumin (ALB).
conclusionThere is a certain risk of liver injury in Chinese patients with COVID-19, and the risk and degree of liver injury are related to the severity of COVID-19.
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