Evidence map›Paper›PMID 33530042›Full record

ArticleNeurosciences (Riyadh, Saudi Arabia)2021

Decreased serum uric acid in patients with traumatic brain injury or after cerebral tumor surgery.

Miao He, Jianqiao Zheng, Hao Liu, Ying Wu, Xinsheng Xue, Chaoran Wu, Huiping Li

Open access · diamondAbstract read
In one paragraph

Article in Neurosciences (Riyadh, Saudi Arabia), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 54% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Trial
  2. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Miao HeFrom the Department of Anesthesiology (He, Zheng, Wu), Department of Neurosurgery (Liu), Department of Neurology (Wu), Department of Critical Care Medicine (Xue), West China Hospital of Sichuan University, Sichuan, China.
Jianqiao ZhengFrom the Department of Anesthesiology (He, Zheng, Wu), Department of Neurosurgery (Liu), Department of Neurology (Wu), Department of Critical Care Medicine (Xue), West China Hospital of Sichuan University, Sichuan, China.
Hao LiuFrom the Department of Anesthesiology (He, Zheng, Wu), Department of Neurosurgery (Liu), Department of Neurology (Wu), Department of Critical Care Medicine (Xue), West China Hospital of Sichuan University, Sichuan, China.
Ying WuFrom the Department of Anesthesiology (He, Zheng, Wu), Department of Neurosurgery (Liu), Department of Neurology (Wu), Department of Critical Care Medicine (Xue), West China Hospital of Sichuan University, Sichuan, China.
Xinsheng XueFrom the Department of Anesthesiology (He, Zheng, Wu), Department of Neurosurgery (Liu), Department of Neurology (Wu), Department of Critical Care Medicine (Xue), West China Hospital of Sichuan University, Sichuan, China.
Chaoran WuFrom the Department of Anesthesiology (He, Zheng, Wu), Department of Neurosurgery (Liu), Department of Neurology (Wu), Department of Critical Care Medicine (Xue), West China Hospital of Sichuan University, Sichuan, China.
Huiping LiFrom the Department of Anesthesiology (He, Zheng, Wu), Department of Neurosurgery (Liu), Department of Neurology (Wu), Department of Critical Care Medicine (Xue), West China Hospital of Sichuan University, Sichuan, China.
Sichuan University · CNWest China Hospital of Sichuan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo investigate changes in sUA in patients with TBI or patients after cerebral tumor surgery and the possible mechanism of these changes.

methodsThis prospective cohort study enrolled patients with TBI or underwent cerebral tumor surgery at West China Hospital, China, from November 2014 to May 2018. Serum UA (sUA) levels, urine excretion, UA oxidant product allantoin and other clinical parameters were assessed.

results100 patients were enrolled for analysis. sUA in patients with TBI or underwent cerebral tumor surgery started to decline from day 1 after injury or surgery compared to control. This decreasing trend continued from day 3 (143.2±59.3 μmol/L, 188.8±49.4 μmol/L vs 287.3±80.2 μmol/L,

conclusionThe sUA was decreased in patients with TBI or underwent cerebral tumor surgery.

Indexed as

AdultAgedBrain Injuries, TraumaticBrain NeoplasmsFemaleHumansMaleMiddle AgedPostoperative PeriodProspective StudiesUric AcidYoung AdultUric Acid

Identifiers

PMID33530042
PMCPMC8015494
OpenAlexW3127934209

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.