Evidence map›Paper›PMID 33529705›Full record

ArticleInternational journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases2021

Dynamical characteristics of the COVID-19 epidemic: Estimation from cases in Colombia.

Hernando Diaz, Guido España, Nelson Castañeda, Laura Rodriguez, Fernando de la Hoz-Restrepo

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Article in International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

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0cells of the map it votes in
5citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Hernando DiazUniversidad Nacional de Colombia, Bogotá, Colombia. Electronic address: hdiazmo@unal.edu.co.
Guido EspañaUniversity of Notre Dame, Notre Dame, IN, USA.
Nelson CastañedaEscuela Tecnológica Instituto Técnico Central, Bogotá, Colombia.
Laura RodriguezGCFEP - Universidad del Tolima, Ibagué, Colombia.
Fernando de la Hoz-RestrepoUniversidad Nacional de Colombia, Bogotá, Colombia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo characterize the dynamics of the coronavirus disease 2019 (COVID-19) epidemic, for modeling purposes.

methodsData from Colombian official case information were collated for a period of 5 months. Dynamical parameters of the disease spread were then estimated from the data. Probability distribution models were identified, representing the time from symptom onset to hospitalization, to intensive care unit (ICU) admission, and to death. Kaplan-Meier estimates were also computed for the probability of eventually requiring hospitalization, needing ICU attention, and dying from the disease (the case fatality ratio).

resultsProbability distributions of the times and probabilities were computed for the population and for groups based on age and sex. The results showed that for the times that characterize the course of the disease for a given patient (time to hospitalization, ICU admission, or death), the variation from one age group to another was very small (around 10% of the fixed effect intercept) and the effect of sex was even smaller (around 1%). The course of the disease appeared to be very similar for all patients. On the other hand, the probability that a patient would advance from one stage of the disease to another (to hospitalization, ICU admission, or death) was heavily influenced by sex and age. The relative risk of death for male individuals was 1.7 times that of female individuals (based on 22 924 deaths).

conclusionsThe times from one stage of the disease to another were almost independent of the major patient variables (sex, age). This was in stark contrast to the probabilities of progressing from one stage to another, which showed a strong dependence on age and sex. Data also showed that the length of hospital and ICU stays were almost independent of sex and age. The only factor that affected this length was the eventual outcome of the disease (survival or death); the time was significantly longer for surviving patients.

Indexed as

SARS-CoV-2AdolescentAdultAgedAged, 80 and overChildChild, PreschoolColombiaCOVID-19EpidemicsFemaleHospitalizationHumansInfantInfant, NewbornIntensive Care UnitsCase fatality ratioColombiaCourse of diseaseCOVID-19Epidemic dynamics

Identifiers

PMID33529705
PMCPMC7846888

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.