ArticleAmerican journal of ophthalmology2021
Relationship between Retinal Vascular Occlusions and Cognitive Dementia in a Large Cross-Sectional Cohort.
Article in American journal of ophthalmology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.
- Does retinal vascular occlusion increase the risk of dementia? A pioneering systematic review and meta-analysis.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025Pooled it
- Retinal Artery Occlusion and Incident Dementia in the All of Us Research Program: Detection Bias Calibration with Prespecified Negative-Control Outcomes.Journal of clinical medicine research · 2026Article
- Use of retinal ischemic perivascular lesions (RIPLS) as a biomarker for cardiovascular disease - a systematic review and meta-analysis.International journal of retina and vitreous · 2025Review
- Retinal Ischemic Perivascular Lesions: An Exploratory Study of Their Potential as Biomarkers for Cardiovascular Disease.Journal of clinical medicine · 2025Article
- Associations Between Retinal Vascular Occlusions and Dementia.Healthcare (Basel, Switzerland) · 2024Article
- Assessing Risk Factors for Cognitive Decline Using Electronic Health Record Data: A Scoping Review.Research square · 2024Article
- Retinal artery occlusion does not act as an independent marker of upcoming dementia: results from a Danish 20-year cohort study.International journal of retina and vitreous · 2023Article
- Retinal vein occlusion is associated with stroke independent of underlying cardiovascular disease.Eye (London, England) · 2023Article
- Risk Factors and Treatment Strategy for Retinal Vascular Occlusive Diseases.Journal of clinical medicine · 2022Review
- Prevalence of subclinical retinal ischemia in patients with cardiovascular disease - a hypothesis driven study.EClinicalMedicine · 2021Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
purposeTo examine the association between cognitive dementia and retinal vascular occlusions.
designA retrospective, cross-sectional study.
methodsSingle-institution study population: we reviewed the electronic medical records of 37,208 individuals older than 65 years of age who were evaluated by an ophthalmologist or an optometrist and who also had a medical visit to our institution over a 6-year period. Individuals with and without retinal vascular occlusions were identified by International Classification of Diseases, version 10 (ICD-10) diagnostic codes. MAIN OUTCOME: we analyzed the association between dementia and retinal vascular occlusions after adjusting for covariates which included age, sex, stroke, diabetes mellitus, and hypertension using multiple logistic regression analyses.
resultsCompared to subjects without retinal vascular occlusions, those with retinal vascular occlusions had a higher prevalence of dementia (6.7% vs. 9.3%, respectively; P < .001). After adjusting for either age or stroke, there were no significant associations between retinal vascular occlusions and dementia.
conclusionsIndividuals with retinal vascular occlusions have a higher prevalence of dementia. However, this association is secondary to shared underlying risk factors in this population, such as older age and stroke.
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