ArticleProceedings. Biological sciences2021
Elevated temperature increases genome-wide selection on de novo mutations.
Article in Proceedings. Biological sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 59 citations in OpenAlex.
- Virulent Parasites Emerge in Hosts With Rising Temperatures.Global change biology · 2026Article
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- Climate-mediated evolution of fungicide resistance: insights from interaction among Phytophthora infestans Cyt-bBMC microbiology · 2025Article
- Effects of Extreme Climatic Events on Evolutionary Processes.Global change biology · 2025Review
- The reliability of environmental cues shape learning and selection against deleterious alleles in seed beetles.Proceedings. Biological sciences · 2025Article
- Repeatability of evolution and genomic predictions of temperature adaptation in seed beetles.Nature ecology & evolution · 2025Article
- Life-history adaptation under climate warming magnifies the agricultural footprint of a cosmopolitan insect pest.Nature communications · 2025Article
- Warmer is better for evolutionary rescue, driving a warm-to-cold bias in habitat colonization dynamics.Proceedings. Biological sciences · 2024Article
- Coevolution of longevity and female germline maintenance.Proceedings. Biological sciences · 2024Article
- When and how can we predict adaptive responses to climate change?Evolution letters · 2024Article
- Heat stress reveals a fertility debt owing to postcopulatory sexual selection.Evolution letters · 2024Article
- Genomic estimates of mutation and substitution rates contradict the evolutionary speed hypothesis of the latitudinal diversity gradient.Proceedings. Biological sciences · 2023Article
- Developmental bias predicts 60 million years of wing shape evolution.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- Mitochondrial Genome Contributes to the Thermal Adaptation of the OomyceteFrontiers in microbiology · 2022Article
- Inbreeding reduces fitness of seed beetles under thermal stress.Journal of evolutionary biology · 2021Article
- Climatic Alterations Influence Bacterial Growth, Biofilm Production and Antimicrobial Resistance Profiles inAntibiotics (Basel, Switzerland) · 2021Article
- Consequences of mutation accumulation for growth performance are more likely to be resource-dependent at higher temperatures.BMC ecology and evolution · 2021Article
- Fitness effects of spontaneous mutations in a warming world.Evolution; international journal of organic evolution · 2021Article
- Elevated temperature increases genome-wide selection on de novo mutations.Proceedings. Biological sciences · 2021Article
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Adaptation in new environments depends on the amount of genetic variation available for evolution, and the efficacy by which natural selection discriminates among this variation. However, whether some ecological factors reveal more genetic variation, or impose stronger selection pressures than others, is typically not known. Here, we apply the enzyme kinetic theory to show that rising global temperatures are predicted to intensify natural selection throughout the genome by increasing the effects of DNA sequence variation on protein stability. We test this prediction by (i) estimating temperature-dependent fitness effects of induced mutations in seed beetles adapted to ancestral or elevated temperature, and (ii) calculate 100 paired selection estimates on mutations in benign versus stressful environments from unicellular and multicellular organisms. Environmental stress
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