Evidence map›Paper›PMID 33529391›Full record

ArticleVox sanguinis2021

Association of the ABO blood group with SARS-CoV-2 infection in a community with low infection rate.

Taiwo R Kotila, Temitope O Alonge, Adeola Fowotade, Olufisayo I Famuyiwa, Adebola S Akinbile

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Vox sanguinis, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Taiwo R KotilaDepartment of Haematology, College of Medicine, University of Ibadan, Nigeria.ORCID https://orcid.org/0000-0001-7355-7166
Temitope O AlongeDepartment of Orthopaedics and Trauma, College of Medicine, University of Ibadan, Nigeria.
Adeola FowotadeClinical Virology Unit, Medical Microbiology and Parasitology Department and Biorepository and Clinical Virology Laboratory, College of Medicine, University of Ibadan, Nigeria.
Olufisayo I FamuyiwaDepartment of Chemical Pathology, University College Hospital, Ibadan, Nigeria.
Adebola S AkinbileOyo State Ministry of Health, Ibadan, Nigeria.
University of Ibadan · NGUniversity College Hospital, Ibadan · NG

Funding

Oyo State Ministry of Health, Ibadan, Nigeria
6 · The paper itself

Abstract

BACKGROUND AND

objectivesReports on the association of the ABO phenotypes with infection by the SARS-CoV-2 virus have mostly come from countries with high infection rates. This study examined the possible association between SARS-CoV-2 infection and the ABO phenotype in Black Africa. MATERIALS AND

methodsThis report is from a single centre where both asymptomatic and symptomatic patients were quarantined. At the time of this report, Oyo State, Nigeria had carried out 15 733 tests of which 3119 were positive for the virus with 1952 recoveries and 37 deaths. The ABO distribution of patients was compared with that of a blood donor population.

resultsOf the 302 participants, 297 (98%) had their blood group determined, asymptomatic and symptomatic individuals were 123 (40·7%) and 179 (59·3%) respectively. Blood group O was significantly less represented among the patients (P < 0·01) while blood groups B and AB were significantly more represented (P < 0·01, P = 0·03 respectively). Patients with anti-B (groups A and O) were significantly less represented than those without anti-B (B and/or AB): B and AB (P < 0·001), B (P = 0·002), AB (P = 0·01). There was no difference in the blood group distribution of symptomatic and asymptomatic patients (χ

conclusionThe higher prevalence of blood group O and more potent beta haemolysins (anti-B antibodies) are likely reasons for the lower infectivity by the SARS-CoV-2 virus and severity of COVID-19 disease in the community.

Indexed as

ABO Blood-Group SystemCOVID-19Blood DonorsHumansSARS-CoV-2ABO Blood-Group Systemantibodiesblood groupCOVID-19haemolysinisoagglutininsserology

Identifiers

PMID33529391
PMCPMC8014178
OpenAlexW3128950634

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.