Evidence map›Paper›PMID 33529256›Full record

Trial reportPloS one2021

Assessing the impact of group antenatal care on gestational length in Rwanda: A cluster-randomized trial.

Felix Sayinzoga, Tiffany Lundeen, Sabine F Musange, Elizabeth Butrick, David Nzeyimana, Nathalie Murindahabi, Hana Azman-Firdaus, Nancy L Sloan, Alejandra Benitez, Beth Phillips and 2 more

Registry-linked trialOpen access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03154177 (Group Antenatal/Postnatal Care in Rwanda), which is not on this map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
6.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03154177 nacompletednot on this map

Group Antenatal/Postnatal Care in Rwanda: a Cluster Randomized Control Trial (RCT) to Measure Its Effectiveness on Increasing Gestational Age, Mortality Among Preterm and Low Birth Weight Infants

TypeinterventionalSponsorUniversity of California, San FranciscoRan2017 to 2019Enrolled26,381ConditionsPregnancy Complications, Preterm Birth, Preterm Labor, StillbirthArmsGroup ANC/PNC, Ultrasound+Pregnancy Testing
3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 23 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 2 countries.

Felix SayinzogaMaternal, Child, and Community Health Division, Rwanda Biomedical Center, Kigali, Rwanda.
Tiffany LundeenInstitute for Global Health Sciences, University of California San Francisco, San Francisco, California, United States of America.ORCID 0000-0002-7039-6253
Sabine F MusangeSchool of Public Health, University of Rwanda, Kigali, Rwanda.ORCID 0000-0001-5988-8874
Elizabeth ButrickInstitute for Global Health Sciences, University of California San Francisco, San Francisco, California, United States of America.
David NzeyimanaSchool of Public Health, University of Rwanda, Kigali, Rwanda.ORCID 0000-0002-1389-7107
Nathalie MurindahabiSchool of Public Health, University of Rwanda, Kigali, Rwanda.
Hana Azman-FirdausInstitute for Global Health Sciences, University of California San Francisco, San Francisco, California, United States of America.
Nancy L SloanInstitute for Global Health Sciences, University of California San Francisco, San Francisco, California, United States of America.
Alejandra BenitezDepartment of Biostatistics, University of California Berkeley, Berkeley, California, United States of America.
Beth PhillipsInstitute for Global Health Sciences, University of California San Francisco, San Francisco, California, United States of America.
Rakesh GhoshInstitute for Global Health Sciences, University of California San Francisco, San Francisco, California, United States of America.
Dilys WalkerInstitute for Global Health Sciences, University of California San Francisco, San Francisco, California, United States of America.
University of California, San Francisco · USUniversity of Kigali · RWRwanda Biomedical Center · RWUniversity of California, Berkeley · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundResearch on group antenatal care in low- and middle-income contexts suggests high acceptability and preliminary implementation success.

methodsWe studied the effect of group antenatal care on gestational age at birth among women in Rwanda, hypothesizing that participation would increase mean gestational length. For this unblinded cluster randomized trial, 36 health centers were pair-matched and randomized; half continued individual antenatal care (control), half implemented group antenatal care (intervention). Women who initiated antenatal care between May 2017 and December 2018 were invited to participate, and included in analyses if they presented before 24 weeks gestation, attended at least two visits, and their birth outcome was obtained. We used a generalized estimating equations model for analysis.

findingsIn total, 4091 women in 18 control clusters and 4752 women in 18 intervention clusters were included in the analysis. On average, women attended three total antenatal care visits. Gestational length was equivalent in the intervention and control groups (39.3 weeks (SD 1.6) and 39.3 weeks (SD 1.5)). There were no significant differences between groups in secondary outcomes except that more women in control sites attended postnatal care visits (40.1% versus 29.7%, p = 0.003) and more women in intervention sites attended at least three total antenatal care visits (80.7% versus 71.7%, p = 0.003). No harms were observed.

interpretationGroup antenatal care did not result in a difference in gestational length between groups. This may be due to the low intervention dose. We suggest studies of both the effectiveness and costs of higher doses of group antenatal care among women at higher risk of preterm birth. We observed threats to group care due to facility staff shortages; we recommend studies in which antenatal care providers are exclusively allocated to group antenatal care during visits.

trial registrationClinicalTrials.gov NCT03154177.

Indexed as

Prenatal CareAdultFemaleGestational AgeHumansPregnancyPremature BirthRwandaYoung Adult

Identifiers

PMID33529256
PMCPMC7853466
OpenAlexW3128509090

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.