Evidence map›Paper›PMID 33529169›Full record

ReviewThe Journal of clinical investigation2021

Turning lead into gold: reprogramming retinal cells to cure blindness.

Seth Blackshaw, Joshua R Sanes

Open access · bronzeAbstract readReview
In one paragraph

Review in The Journal of clinical investigation, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
3.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 52 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. The Healthy and Diseased Retina Seen through Neuron-Glia Interactions.International journal of molecular sciences · 2024
    Review
  8. Review
  9. Article
  10. Cell-Based Therapies: Strategies for Regeneration.Cold Spring Harbor perspectives in medicine · 2023
    Review
  11. Review
  12. In vivo cell fate reprogramming for spinal cord repair.Current opinion in genetics & development · 2023
    Review
  13. Review
  14. Direct neuronal reprogramming by temporal identity factors.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  15. Review
  16. Neural regeneration research · 2023
    Review
  17. Review
  18. Advances in the study of Müller glia reprogramming in mammals.Frontiers in cellular neuroscience · 2023
    Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Seth BlackshawDepartments of Neuroscience.
Joshua R SanesCenter for Brain Science and.
Harvard University · USJohns Hopkins University · US

Funding

Transcriptional regulation of retinal cell differentiation and functionR01EY020560 · NEI · JOHNS HOPKINS UNIVERSITY · PI BLACKSHAW, SETH · 2011 to 2021
$4.4M
Identification of gene regulatory networks that control proliferative and neurogenic competence in mammalian Müller gliaR01EY031685 · NEI · JOHNS HOPKINS UNIVERSITY · PI BLACKSHAW, SETH · 2020 to 2023
$2.0M
NEI NIH HHS R01 EY020560NEI NIH HHS R01 EY031685
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Cellular ReprogrammingBlindnessHumansMacular DegenerationRetinal Ganglion CellsUnited States

Identifiers

PMID33529169
PMCPMC7843217
OpenAlexW3126216907

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.