Evidence map›Paper›PMID 33529151›Full record

ArticleeLife2021

Celsr1 adhesive interactions mediate the asymmetric organization of planar polarity complexes.

Sara N Stahley, Lena P Basta, Rishabh Sharan, Danelle Devenport

Open access · goldAbstract read
In one paragraph

Article in eLife, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 49 citations in OpenAlex.

  1. Article
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  6. The far extracellular CUB domain of the adhesion GPCR ADGRG6/GPR126 is a key regulator of receptor signaling.Proceedings of the National Academy of Sciences of the United States of America · 2025
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  14. A quick guide to (transmembrane) planar cell polarity mouse strains.Nature reviews. Molecular cell biology · 2024
    Article
  15. Evaluating Planar Cell Polarity in the Developing Mouse Epidermis.Methods in molecular biology (Clifton, N.J.) · 2024
    Article
  16. Article
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  20. Antiparallel dimer structure of CELSR cadherin in solution revealed by high-speed atomic force microscopy.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Sara N StahleyDepartment of Molecular Biology, Princeton University, Princeton, United States.ORCID 0000-0002-2316-8354
Lena P BastaDepartment of Molecular Biology, Princeton University, Princeton, United States.
Rishabh SharanDepartment of Molecular Biology, Princeton University, Princeton, United States.
Danelle DevenportDepartment of Molecular Biology, Princeton University, Princeton, United States.ORCID 0000-0002-5464-259X
Princeton University · US

Funding

Multiscale coordination of planar cell polarityR01AR066070 · NIAMS · PRINCETON UNIVERSITY · PI DEVENPORT, DANELLE N · 2015 to 2025
$5.7M
Cell-cycle control of cell polarity in epidermal patterning and differentiationR01AR068320 · NIAMS · PRINCETON UNIVERSITY · PI Danelle N Devenport · 2016 to 2026
$3.8M
Celsr1-mediated planar cell polarity: defining the adhesive interface and mechanisms of asymmetryF32AR071764 · NIAMS · PRINCETON UNIVERSITY · PI STAHLEY, SARA N · 2017 to 2019
$178k
NIAMS NIH HHS F32 AR071764NIAMS NIH HHS R01 AR066070NIAMS NIH HHS R01 AR068320NIH HHS F32AR071764NIH HHS R01AR068320
6 · The paper itself

Abstract

To orchestrate collective polarization across tissues, planar cell polarity (PCP) proteins localize asymmetrically to cell junctions, a conserved feature of PCP that requires the atypical cadherin Celsr1. We report that mouse Celsr1 engages in both

Indexed as

AnimalsCell LineCell PolarityEmbryo, MammalianFemaleFrizzled ReceptorsHumansKeratinocytesMaleMiceReceptors, G-Protein-CoupledCelsr1 protein, mouseFrizzled ReceptorsReceptors, G-Protein-Coupledcadherincell biologycell junctionsdevelopmental biologyepidermisepitheliamouseplanar cell polaritysuper resolution microscopy

Identifiers

PMID33529151
PMCPMC7857726
OpenAlexW3126780574

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.