Evidence map›Paper›PMID 33528997›Full record

ArticleAnalytical chemistry2021

Isolation of Natural DNA Aptamers for Challenging Small-Molecule Targets, Cannabinoids.

Haixiang Yu, Yingping Luo, Obtin Alkhamis, Juan Canoura, Boyang Yu, Yi Xiao

Open access · greenAbstract read
In one paragraph

Article in Analytical chemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
4.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 69 citations in OpenAlex.

  1. Article
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  3. Advances in aptamer technology for target-based drug discovery.Journal of pharmaceutical analysis · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Haixiang YuDepartment of Chemistry and Biochemistry, Florida International University, 11200 SW 8th Street, Miami, Florida, 33199, United States.
Yingping LuoDepartment of Chemistry and Biochemistry, Florida International University, 11200 SW 8th Street, Miami, Florida, 33199, United States.
Obtin AlkhamisDepartment of Chemistry and Biochemistry, Florida International University, 11200 SW 8th Street, Miami, Florida, 33199, United States.
Juan CanouraDepartment of Chemistry and Biochemistry, Florida International University, 11200 SW 8th Street, Miami, Florida, 33199, United States.
Boyang YuState Key Laboratory of Natural Medicines, Jiangsu Key Laboratory of TCM Evaluation and Translational Research, Department of Complex Prescription of TCM, China Pharmaceutical University, Nanjing 211198, P. R. China.
Yi XiaoDepartment of Chemistry and Biochemistry, Florida International University, 11200 SW 8th Street, Miami, Florida, 33199, United States.ORCID 0000-0001-7278-9811
Florida International University · USChina Pharmaceutical University · CN

Funding

Homogeneous Nuclease-Assisted SELEX for Rapid Isolation of Cross-Reactive, Functionalized Aptamers for Synthetic CannabinoidsR21DA045334 · NIDA · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI XIAO, YI · 2019 to 2020
$334k
NIDA NIH HHS R21 DA045334
6 · The paper itself

Abstract

Aptamers are nucleic acid-based affinity reagents that are isolated via an

Indexed as

Aptamers, NucleotideCannabinoidsGene LibraryLigandsSELEX Aptamer TechniqueAptamers, NucleotideCannabinoidsLigands

Identifiers

PMID33528997
PMCPMC7895305
OpenAlexW3126898688

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.