Evidence map›Paper›PMID 33528881›Full record

ArticleHealth expectations : an international journal of public participation in health care and health policy2021

'What the herbal medicine can do for me in a week, the orthodox does in a year': Perceived efficacy of local alternative therapies influences medication adherence in patients with atherosclerotic cardiovascular disease.

Amos Laar, Ernest Amoah Ampah, Yolanda Fernandez, Gideon Senyo Amevinya, Priscillia Nortey, Frank Benyah, Joseph Akamah, Marcella Ambenne, Peter Lamptey, Caroline Free and 2 more

Open access · goldAbstract read
In one paragraph

Article in Health expectations : an international journal of public participation in health care and health policy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.4field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 2 countries.

Amos LaarDepartment of Population, Family, & Reproductive Health, School of Public Health, University of Ghana, Legon, Accra, Ghana.ORCID 0000-0001-5557-0164
Ernest Amoah AmpahHouse of Mentoring and Research Resources (HM2R). Box LG 1099, University Post Office, Legon, Accra, Ghana.
Yolanda FernandezDepartment of Non-communicable Disease Epidemiology, Faculty of Epidemiology and Population Health, London School of Hygiene & Tropical Medicine. Keppel St, London, UK.
Gideon Senyo AmevinyaDepartment of Population, Family, & Reproductive Health, School of Public Health, University of Ghana, Legon, Accra, Ghana.
Priscillia NorteyDepartment of Epidemiology and Disease Control, School of Public Health Box LG 13, University of Ghana, Legon, Accra, Ghana.
Frank BenyahThe Ghana Police Hospital, Accra, Ghana.
Joseph AkamahDepartment of Medicine and Therapeutics, Divisions of Cardiology and Neurology, School of Medicine and Dentistry, University of Ghana, Korle-Bu, Ghana.
Marcella AmbenneHouse of Mentoring and Research Resources (HM2R). Box LG 1099, University Post Office, Legon, Accra, Ghana.
Peter LampteyDepartment of Non-communicable Disease Epidemiology, Faculty of Epidemiology and Population Health, London School of Hygiene & Tropical Medicine. Keppel St, London, UK.
Caroline FreeDepartment of Population Health, Faculty of Epidemiology and Population Health, London School of Hygiene & Tropical Medicine Keppel St, London, UK.
Helena Legido-QuigleyDepartment of Non-communicable Disease Epidemiology, Faculty of Epidemiology and Population Health, London School of Hygiene & Tropical Medicine. Keppel St, London, UK.
Pablo PerelDepartment of Non-communicable Disease Epidemiology, Faculty of Epidemiology and Population Health, London School of Hygiene & Tropical Medicine. Keppel St, London, UK.
University of Ghana · GHLondon School of Hygiene & Tropical Medicine · GB37 Military Hospital · GHUniversity of London · GB

Funding

Medical Research Council MR/N021304/1Wellcome Trust
6 · The paper itself

Abstract

backgroundThere is strong evidence that anti-platelet therapy, ACE inhibitors, beta-blockers and statins are cost-effective in reducing subsequent cardiovascular disease (CVD) events in patients with atherosclerotic cardiovascular disease (ACVD). In some settings, only a low proportion of people have access to these medications, and even lower adhere to them. The current study explored and presents data on the causes of poor adherence to orthodox medication and motivations for alternative therapies in patients with established atherosclerotic cardiovascular disease (ACVD).

methodsThe study was conducted among city-dwelling adults with ACVD in Accra - Ghana's capital city. Eighteen interviews were conducted with patients with established ACVD. A follow-up focus group discussion was conducted with some of them. The protocol was approved by two ethics review committees based in Ghana and in the United Kingdom. All participants were interviewed after informed consent. Analysis was done with the Nvivo qualitative data analysis software.

resultsWe identified motivations for use of alternatives to orthodox therapies. These cover the five dimensions of adherence: social and economic, health-care system, condition-related, therapy-related, and patient-related dimensions. Perceived inability of an orthodox medication to provide immediate benefit is an important motivator for use of alternative forms of medication.

conclusionsA multiplicity of factors precipitate non-adherence to orthodox therapies. Perceived efficacy and easy access to local alternative therapies such as herbal and faith-based therapies are important motivators.

Indexed as

Cardiovascular DiseasesComplementary TherapiesAdultHerbal MedicineHumansMedication AdherenceUnited Kingdomatherosclerotic cardiovascular diseasefaith-based healingGhanaherbal therapiesNon-adherenceorthodox medicationqualitative research

Identifiers

PMID33528881
PMCPMC8077140
OpenAlexW3129167336

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.