ArticleJournal of behavioral medicine2021
Misinformation and other elements in HPV vaccine tweets: an experimental comparison.
Article in Journal of behavioral medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.
- Interventions Addressing Vaccine Hesitancy in the WHO European Region and in North America (United States and Canada): A Systematic Review.Public health reviews · 2026Pooled it
- Research Trends and Gaps in Human Papillomavirus Vaccination Intention in South Korea: A Scoping Review.Healthcare (Basel, Switzerland) · 2026Review
- Urban-rural disparities in HPV vaccination knowledge, willingness, and uptake among women in the Tibet autonomous region: a multi-center cross-sectional study.Frontiers in public health · 2026Article
- HPV Vaccination in the U.S. Midwest: Barriers and Facilitators of Initiation and Completion in Adolescents and Young Adults.Vaccines · 2025Article
- Overcoming HPV Vaccine Hesitancy in Japan: A Narrative Review of Safety Evidence, Risk Communication, and Policy Approaches.Vaccines · 2025Review
- The Role of Internet Information on Anti-HPV Vaccines: A Comprehensive Overview of a Double-Edged Sword.Vaccines · 2025Review
- HPV vaccine misinformation on social media: A multi-method qualitative analysis of comments across three platforms.PEC innovation · 2024Article
- Longitudinal analysis of behavioral factors and techniques used to identify vaccine hesitancy among Twitter users: Scoping review.Human vaccines & immunotherapeutics · 2023Article
- Fact-Checking Cancer Information on Social Media in Japan: Retrospective Study Using Twitter.JMIR formative research · 2023Article
- Development of a Tailored Mobile Phone-Based Intervention to Facilitate Parent-Child Communication and Build Human Papillomavirus Vaccine Confidence: Formative Qualitative Study.JMIR formative research · 2023Article
- Scaling up the discovery of hesitancy profiles by identifying the framing of beliefs towards vaccine confidence in Twitter discourse.Journal of behavioral medicine · 2023Article
- Characterizing U.S. mothers with high human papillomavirus vaccine intent yet unvaccinated adolescents.Preventive medicine · 2023Article
- HPV and COVID-19 vaccines: Social media use, confidence, and intentions among parents living in different community types in the United States.Journal of behavioral medicine · 2023Article
- COVID-19 vaccine uptake and attitudes towards mandates in a nationally representative U.S. sample.Journal of behavioral medicine · 2023Article
- Do social media campaigns foster vaccination adherence? A systematic review of prior intervention-based campaigns on social media.Telematics and informatics · 2023Review
- Associations Between Human Papillomavirus Vaccine Decisions and Exposure to Vaccine Information in Social Media.Cancer control : journal of the Moffitt Cancer CenterArticle
- An Evaluation of Messages to Promote Parental Intent to Vaccinate Children Aged <12 Years Against COVID-19.Public health reports (Washington, D.C. : 1974)Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
Abstract
Our study examined how misinformation and other elements of social media messages affect antecedents to human papillomavirus (HPV) vaccination of adolescents. In 2017-2018, we randomly assigned a national sample of 1206 U.S. parents of adolescents to view one tweet using a 2 × 2 × 2 × 2 between-subjects factorial experiment. The 16 experimental tweets varied four messaging elements: misinformation (misinformation or not), source (person or organization), narrative style (storytelling or scientific data), and topic (effectiveness or safety). Parents reported their motivation to vaccinate (primary outcome), trust in social media content, and perceived risk about HPV-related diseases. Tweets without misinformation elicited higher HPV vaccine motivation than tweets with misinformation (25% vs. 5%, OR = 6.60, 95% CI:4.05, 10.75). Motivation was higher for tweets from organizations versus persons (20% vs. 10%, OR = 2.47, 95% CI:1.52, 4.03) and about effectiveness versus safety (20% vs. 10%, OR = 2.03, 95% CI:1.24, 3.30). Tweets with misinformation produced lower trust and higher perceived risk (both p < .01), with impact varying depending on source and topic. In conclusion, misinformation was the most potent social media messaging element. It may undermine progress in HPV vaccination.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.