ArticleGenes & genomics2021
Transcriptome reveals genes involving in black skin color formation of ducks.
Article in Genes & genomics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 17 citations in OpenAlex.
- Melanin and Neurotransmitter Signalling Genes Are Differentially Co-Expressed in Growing Feathers of White and Rufous Barn Owls.Pigment cell & melanoma research · 2025Article
- Understanding the skin blackening phenomenon in Youzhou Dark goats based on the histological characteristics of melanocytes.Journal of advanced veterinary and animal research · 2024Article
- Identification and Validation of Magnolol Biosynthesis Genes inMolecules (Basel, Switzerland) · 2024Article
- Identification of SNPs inFrontiers in genetics · 2023Article
- Identification of key sex-specific pathways and genes in the subcutaneous adipose tissue from pigs using WGCNA method.BMC genomic data · 2022Article
Corrections and comments
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Authors and funding
13 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSkin color is colorful for birds, which has been reported to be associated with multi-biological functions, such as crypsis, camouflage, social signaling and mate choice, but little is known about its underlying molecular mechanism.
objectiveStudies on the major genes affecting the black skin color of ducks.
methodsFor this purpose, Silver ammonia staining and RNA-seq analysis were carried out to identify the differences in tissue morphology and gene expressions between black and yellow skin ducks.
resultsThe silver ammonia dyes slice results showed that in the development of black duck, the content of melanin in black skin gradually increased and then decreased, and the content of melanin in yellow and black skin was significantly different. Through transcriptome, a total of 102 and 84 differentially expressed genes (DEGs) were identified in beak skin and web skin, respectively. These DEGs were enriched in melanin biosynthesis and play a critical role in melanogenesis pathway. Co-expression analysis showed that EDNRB2 was the only gene associated with black skin color in DEGs, which was also consistent with qRT-PCR.
conclusionsThe melanin synthesis pathway dominated by EDNRB2 up-regulated the amount of melanin synthesis, leading to the formation of black skin in ducks.
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