Evidence map›Paper›PMID 33528009›Full record

ArticleJournal of the Pediatric Infectious Diseases Society2021

Variability in Ceftriaxone Dosing Across 32 US Acute Care Children's Hospitals.

Rina A Ferguson, Joshua C Herigon, Brian R Lee, Mari M Nakamura, Jason G Newland

Abstract read
In one paragraph

Article in Journal of the Pediatric Infectious Diseases Society, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. A Cautionary Tale of Combination Ceftriaxone and Lansoprazole: Should Pediatric Clinicians Heed the Warning?The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Rina A FergusonDepartment of Pediatrics, Washington University in St Louis, St Louis, Missouri, USA.ORCID 0000-0001-8923-9103
Joshua C HerigonDepartment of Pediatrics, Division of Infectious Diseases, Boston Children's Hospital, Boston, Massachusetts, USA.
Brian R LeeHealth Services and Outcomes Research, Children's Mercy Kansas City, Kansas City, Missouri, USA.
Mari M NakamuraDepartment of Pediatrics, Division of Infectious Diseases, Boston Children's Hospital, Boston, Massachusetts, USA.
Jason G NewlandDepartment of Pediatrics, Washington University in St Louis, St Louis, Missouri, USA.

Funding

RESEARCH TRAINING-MEDICAL INFORMATICS 90T15LM007092 · NLM · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI Nils Gehlenborg · 1992 to 2026
$32.8M
NLM NIH HHS T15 LM007092
6 · The paper itself

Abstract

Ceftriaxone is one of the most common antibiotics prescribed for hospitalized children in the United States. However, ceftriaxone is not dosed consistently. Sepsis/serious bacterial infection had high dosing variability. Dosing for central nervous system infection was frequently suboptimal. Future efforts should focus on optimizing and standardizing ceftriaxone dosing.

Indexed as

Bacterial InfectionsCeftriaxoneAnti-Bacterial AgentsChildChild, HospitalizedHospitalsHumansUnited StatesAnti-Bacterial AgentsCeftriaxoneantibiotic dosingceftriaxoneinpatient antimicrobial stewardshiptherapeutic dosingweight-based dosing

Identifiers

PMID33528009
PMCPMC8163046

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.