Evidence map›Paper›PMID 33528006›Full record

ArticleBiostatistics (Oxford, England)2022

Efficiently transporting causal direct and indirect effects to new populations under intermediate confounding and with multiple mediators.

Kara E Rudolph, Iván Díaz

Abstract read
In one paragraph

Article in Biostatistics (Oxford, England), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Kara E RudolphDepartment of Epidemiology, Mailman School of Public Health, Columbia University; and Division of Biostatistics, Department of Population Health Sciences, Weill Cornell Medicine, New York, NY, USA.
Iván DíazDepartment of Epidemiology, Mailman School of Public Health, Columbia University; and Division of Biostatistics, Department of Population Health Sciences, Weill Cornell Medicine, New York, NY, USA.

Funding

Mechanisms linking neighborhood poverty to problematic adolescent drug useR00DA042127 · NIDA · UNIVERSITY OF CALIFORNIA AT DAVIS · PI RUDOLPH, KARA ELIZABETH · 2018 to 2021
$889k
NIDA NIH HHS R00 DA042127
6 · The paper itself

Abstract

The same intervention can produce different effects in different sites. Existing transport mediation estimators can estimate the extent to which such differences can be explained by differences in compositional factors and the mechanisms by which mediating or intermediate variables are produced; however, they are limited to consider a single, binary mediator. We propose novel nonparametric estimators of transported interventional (in)direct effects that consider multiple, high-dimensional mediators and a single, binary intermediate variable. They are multiply robust, efficient, asymptotically normal, and can incorporate data-adaptive estimation of nuisance parameters. They can be applied to understand differences in treatment effects across sites and/or to predict treatment effects in a target site based on outcome data in source sites.

Indexed as

Models, StatisticalCausalityHumansInterventional indirect effectMediationNon-parametric methodsStochastic indirect effectTargeted learning

Identifiers

PMID33528006
PMCPMC9295139

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.