Evidence map›Paper›PMID 33527741›Full record

ArticlePhysiological reports2021

Sexually dimorphic response of mice to the Western-style diet caused by deficiency of fatty acid binding protein 6 (Fabp6).

Salam M Habib, Brittnee L Zwicker, Linda Wykes, Luis B Agellon

Open access · goldAbstract readComparative Study
In one paragraph

Article in Physiological reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 14 citations in OpenAlex.

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  8. Effects ofMetabolites · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Salam M HabibSchool of Human Nutrition, McGill University, Montreal, QC, Canada.
Brittnee L ZwickerSchool of Human Nutrition, McGill University, Montreal, QC, Canada.
Linda WykesSchool of Human Nutrition, McGill University, Montreal, QC, Canada.
Luis B AgellonSchool of Human Nutrition, McGill University, Montreal, QC, Canada.ORCID 0000-0002-2209-8702
McGill University · CA

Funding

CIHR
6 · The paper itself

Abstract

Bile acids are natural detergents that aid in the absorption of dietary lipids. Fatty acid binding protein 6 (Fabp6) is a component of the bile acid recovery system that operates in the small intestine. The aim of this study was to determine if Fabp6 deficiency causes dietary fat malabsorption. Wild-type and Fabp6-deficient mice were fed a Western-style diet (WSD) or a reference low-fat diet (LFD) for 10 weeks. The body weight gain, bile acid excretion, fat excretion, energy metabolism, and major gut microbial phyla of the mice were assessed at the end of the controlled diet period. Fabp6

Indexed as

AdiposityGastrointestinal MicrobiomeIntestinal AbsorptionLipid MetabolismAnimalsBile Acids and SaltsDiet, WesternDysbiosisEnergy MetabolismFatty Acid-Binding ProteinsFemaleGenotypeMalabsorption SyndromesMaleMiceMice, Inbred C57BLBile Acids and SaltsFabp6 protein, mouseFatty Acid-Binding Proteinsbile acid malabsorptionfat malabsorptionfatty acid binding proteingut microbiotaobesitysexual dimorphism

Identifiers

PMID33527741
PMCPMC7851434
OpenAlexW3128000506

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.