Evidence map›Paper›PMID 33527560›Full record

ArticleDermatologic therapy2021

Mask-induced Koebner phenomenon and its clinical phenotypes: A multicenter, real-life study focusing on 873 dermatological consultations during COVID-19 pandemics.

Giovanni Damiani, Laura Cristina Gironi, Khalaf Kridin, Alessia Pacifico, Alessandra Buja, Nicola Luigi Bragazzi, Magdalena Spalkowska, Paolo Daniele Maria Pigatto, Pierachille Santus, Young Dermatologists Italian Network and 1 more

Open access · bronzeAbstract readMulticenter Study
In one paragraph

Article in Dermatologic therapy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
7.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.

  1. Italian Expert Consensus on Clinical and Therapeutic Management of Multiple Chemical Sensitivity (MCS).International journal of environmental research and public health · 2021
    Pooled it
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  9. Review
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  12. Facial Irritant Contact Dermatitis Caused by Pyraclostrobin.Clinical, cosmetic and investigational dermatology · 2022
    Article
  13. Observational
  14. Article
  15. Article
  16. Article
  17. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 7 institutions in 4 countries.

Giovanni DamianiClinical Dermatology, IRCCS Istituto Ortopedico Galeazzi, Milan, Italy.ORCID https://orcid.org/0000-0002-2390-6505
Laura Cristina GironiAOU Maggiore della Carità, Novara, Italy.ORCID https://orcid.org/0000-0002-7298-4446
Khalaf KridinLübeck Institute of Experimental Dermatology, University of Lübeck, Lübeck, Germany.ORCID https://orcid.org/0000-0001-9971-9151
Alessia PacificoClinical Dermatology Department, IRCCS S. Gallicano Dermatological Institute, Rome, Italy.ORCID https://orcid.org/0000-0003-0348-0620
Alessandra BujaDepartment of Cardiac, Thoracic, Vascular Sciences and Public Health, Unit of Hygiene and Public Health, University of Padua, Padua, Italy.
Nicola Luigi BragazziLaboratory for Industrial and Applied Mathematics (LIAM), Department of Mathematics and Statistics, York University, Toronto, Canada.
Magdalena SpalkowskaFaculty of Medicine, Department of Dermatology, Jagellonian University Medical College, Krakow, Poland.
Paolo Daniele Maria PigattoClinical Dermatology, IRCCS Istituto Ortopedico Galeazzi, Milan, Italy.
Pierachille SantusDepartment of Biomedical and Clinical Sciences (DIBIC), Università degli Studi di Milano, Milano, Italy.
Young Dermatologists Italian Network
Paola SavoiaDepartment of Health Sciences, University of Eastern Piedmont, Novara, Italy.
Università degli Studi del Piemonte Orientale “Amedeo Avogadro” · ITUniversity of Milan · ITUniversity of Padua · ITJagiellonian University · PLSan Gallicano Hospital · ITUniversity of Lübeck · DEYork University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

During COVID-19 pandemic, wearing masks for prevention became mandatory but evidence suggest that is also detrimental for skin. Although facial dermatoses due to masks increase in both healthcare workers and general population, a pathogenetic hypothesis remains still elusive. We aimed to evaluate the prevalence of dermatological consultations due to Koebner triggered dermatoses In this prospective, multicenter, real life study carried out in Italy from March 11th to December 11th 2020 during COVID-19 pandemics, dermatological consultations (in-person and telemedicine) to study the prevalence of Koebner (KB) phenomenon due to masks were evaluated. Boyd and Nelder classification was adopted for Koebner phenomenon and Bizzozero's for KB intensity. A total of 229/873 (26.2%) dermatological consultations were KB triggered dermatoses and lesions were located in mask-covered ear area (76 [33.2%]), malar area (73 [31.8%]), perioral area (53 [23.1%]), and nose (27 [11.8%]). The first KB category grouped 142 patients (psoriasis, vitiligo, maskne, and mask rosacea), the second one 24 (warts, molluscum contagiosum, and impetigo), the third one 46 (atopic dermatitis), and the fourth one 17 (eczema). Among previously KB negative psoriatic patients that became KB positive, 9/13 (69.2%) had discontinued or modified the prescribed antipsoriatic treatment. Mask-related Koebner phenomenon is an important clinical sign to orient clinician's therapeutic protocols during COVID-19 pandemic, especially in patients with psoriasis.

Indexed as

COVID-19PandemicsHumansItalyMasksPhenotypeProspective StudiesReferral and ConsultationSARS-CoV-2COVID-19facial dermatosesKoebner clinical phenotypesKoebner mask inducedpersonal protective equipmentpsoriasissurgical maskstelemedicine

Identifiers

PMID33527560
PMCPMC7995036
OpenAlexW3127885124

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.