Evidence map›Paper›PMID 33527304›Full record

ArticleApplied health economics and health policy2021

The Danish EQ-5D-5L Value Set: A Hybrid Model Using cTTO and DCE Data.

Cathrine Elgaard Jensen, Sabrina Storgaard Sørensen, Claire Gudex, Morten Berg Jensen, Kjeld Møller Pedersen, Lars Holger Ehlers

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In one paragraph

Article in Applied health economics and health policy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 103 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
103citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

103 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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  7. The impact of screening-detected atrial fibrillation and associated outcomes on quality of life.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025
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  8. Cost-Effectiveness of Hospital-at-Home and Fecal Microbiota Transplantation in Treating Older Patients With Clostridioides difficile.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2025
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43 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Cathrine Elgaard JensenDepartment of Clinical Medicine, Danish Center for Healthcare Improvements, Aalborg University, Aalborg, Denmark. cathelgaard@gmail.com.ORCID 0000-0001-7300-254X
Sabrina Storgaard SørensenDepartment of Clinical Medicine, Danish Center for Healthcare Improvements, Aalborg University, Aalborg, Denmark.
Claire GudexDepartment of Clinical Research, University of Southern Denmark and OPEN - Open Patient data Explorative Network, Odense University Hospital, Odense, Denmark.
Morten Berg JensenDepartment of Economics and Business Economics, Aarhus University, Aarhus, Denmark.
Kjeld Møller PedersenDepartment of Management and Economics, University of Southern Denmark, Odense, Denmark.
Lars Holger EhlersDepartment of Clinical Medicine, Danish Center for Healthcare Improvements, Aalborg University, Aalborg, Denmark.

Funding

Aase og Ejnar Danielsens Fond 20-000055EuroQol Research Foundation 20170400EuroQol Research Foundation 20170401The Danish Health Foundation 18-B-0187
6 · The paper itself

Abstract

objectivesQuality-adjusted life-years (QALYs) are expected to be used for priority setting of hospital-dispensed medicines in Denmark from 2021. The aim of this study was to develop the first Danish value set for the EQ-5D-5L based on interviews with a representative sample of the Danish adult population.

methodsA nationally representative sample based on age (> 18 years), gender, education, and geographical region was recruited using data provided by Statistics Denmark. Computer-assisted personal interviews were carried out using the EQ-VT 2.1. Respondents each valued ten health states using composite time trade-off (cTTO) and seven health states using discrete-choice experiment (DCE). Different predictive models were explored using cTTO and DCE data alone or in combination as hybrid models. Model performance was assessed using logical consistency.

resultsA total of 1014 interviews were included in the analyses. The sample was representative of the Danish adult population, though the sample contained slightly more respondents with higher education than in the general population. Only the heteroscedastic censored hybrid model combining cTTO and DCE data yielded consistent results, and hence was chosen for modelling the final Danish value set. The predicted values ranged from - 0.757 to 1, and anxiety/depression was the dimension assigned most value by respondents.

conclusionsThis study established the Danish EQ-5D-5L value set, which represents the preferences of the Danish general population, and is expected to provide key input for healthcare decision-making in a Danish context.

Indexed as

Health StatusQuality of LifeAdolescentAdultDenmarkHumansQuality-Adjusted Life YearsSurveys and Questionnaires

Identifiers

PMID33527304
PMCPMC8270796

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.