Evidence map›Paper›PMID 33527218›Full record

ReviewNeurochemical research2021

Astrocyte Mitochondria in White-Matter Injury.

Hung Nguyen, Sarah Zerimech, Selva Baltan

Open access · greenAbstract readReview
In one paragraph

Review in Neurochemical research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Hung Nguyen *Anesthesiology and Peri-Operative Medicine (APOM), Oregon Health and Science University, Portland, OR, 97239, USA.
Sarah Zerimech *Anesthesiology and Peri-Operative Medicine (APOM), Oregon Health and Science University, Portland, OR, 97239, USA.
Selva BaltanAnesthesiology and Peri-Operative Medicine (APOM), Oregon Health and Science University, Portland, OR, 97239, USA. baltan@ohsu.edu.
Oregon Health & Science University · US

Funding

Vulnerability of Aging White Matter to IschemiaR01AG033720 · NIA · UNIVERSITY OF WASHINGTON · PI BALTAN, SELVA · 2010 to 2021
$2.7M
Casein kinase 2 signaling in axonal injuryR21NS094881 · NINDS · CLEVELAND CLINIC LERNER COM-CWRU · PI BALTAN, SELVA · 2016 to 2017
$436k
Vulnerability of Aging White Matter to IschemiaR56AG033720 · NIA · CLEVELAND CLINIC LERNER COM-CWRU · PI BALTAN, SELVA · 2016 to 2016
$396k
NIA NIH HHS AG033720NIA NIH HHS R01 AG033720NIA NIH HHS R56 AG033720NINDS NIH HHS NS094881NINDS NIH HHS R21 NS094881
6 · The paper itself

Abstract

This review summarizes the diverse structure and function of astrocytes to describe the bioenergetic versatility required of astrocytes that are situated at different locations. The intercellular domain of astrocyte mitochondria defines their roles in supporting and regulating astrocyte-neuron coupling and survival against ischemia. The heterogeneity of astrocyte mitochondria, and how subpopulations of astrocyte mitochondria adapt to interact with other glia and regulate axon function, require further investigation. It has become clear that mitochondrial permeability transition pores play a key role in a wide variety of human diseases, whose common pathology may be based on mitochondrial dysfunction triggered by Ca

Indexed as

AnimalsAstrocytesBrain DiseasesHumansMitochondriaNeuronsWhite MatterAstroglial interactionsAxonal degenerationGlial cellsMitochondrial dynamicsNeurodegenerative diseasesNeurovascular injuries

Identifiers

PMID33527218
PMCPMC8935665
OpenAlexW3126659629

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.