ArticleSurgical endoscopy2022
Laparoscopic negative appendectomy during pregnancy is associated with adverse neonatal outcome.
Article in Surgical endoscopy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 9 citations in OpenAlex.
- Preterm Infant and Caregiver Outcomes After Maternal Appendectomy During Pregnancy.Healthcare (Basel, Switzerland) · 2026Article
- Appendectomy During Pregnancy and the Risk of Preterm Birth: A Systematic Review of Contemporary Clinical Studies.Journal of clinical medicine · 2026Review
- Acute appendicitis during pregnancy: a case-control study.Frontiers in surgery · 2026Article
- Magnetic resonance imaging for acute appendicitis in pregnancy: can clinical scores predict when imaging is needed?European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2024Article
- Appendectomy for suspected appendicitis during pregnancy- a retrospective comparative study of 99 pregnant and 1796 non-pregnant women.Langenbeck's archives of surgery · 2024Article
- Open versus laparoscopic appendectomy for acute appendicitis in pregnancy: a population-based study.Surgical endoscopy · 2023Article
- Safety of laparoscopic surgery during pregnancy: a Korean nationwide population-based study.Surgical endoscopy · 2022Article
- Pregnant patients requiring emergency general surgery: a scoping review of diagnostic and management strategies.Canadian journal of surgery. Journal canadien de chirurgieArticle
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe impact on pregnancy of laparoscopy for acute appendicitis is well documented. However, with an accurate pre-operative diagnosis being more challenging in pregnant patients, the incidence of a negative appendectomy (NA) is higher in this cohort. The aim of this study was to evaluate the maternal and neonatal implications of a NA during pregnancy.
methodsA single center retrospective study between 2004 and 2019 was performed. Pregnant women who underwent laparoscopic appendectomy for suspected appendicitis were identified from which those who had a pathologically normal appendix were selected. The maternal and neonatal outcome of this group were compared with a matched control group of pregnant women who underwent diagnostic laparoscopy for a presumed ovarian torsion in whom no further surgical intervention was performed. Multivariate regression analysis was performed to explore factors that gestational size.
resultsOf the 225 pregnant women who underwent laparoscopy appendectomy, a NA was performed in 33 (14.7%). These were compared with 50 pregnant women in the diagnostic laparoscopy group. The former was characterized by higher rate of nulliparity and later gestational age at the time of the surgery (17.8 ± 7.5 vs 11.3 ± 6.3, p < 0.001). Whilst the rate of maternal complications during pregnancy were similar between the groups, NA was associated with significantly lower neonatal birthweights (2733.9 ± 731.1 vs 3200.7 ± 458.5 g, p = 0.002) and a significantly higher risk of small for gestational age (SGA) infants (OR 5.6, 95% CI 1.02-30.9).
conclusionsPerforming a NA during pregnancy is an indicator for perioperative counseling and antenatal follow up.
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