Evidence map›Paper›PMID 33527176›Full record

ArticleEuropean journal of nuclear medicine and molecular imaging2021

Artificial intelligence enables whole-body positron emission tomography scans with minimal radiation exposure.

Yan-Ran Joyce Wang, Lucia Baratto, K Elizabeth Hawk, Ashok J Theruvath, Allison Pribnow, Avnesh S Thakor, Sergios Gatidis, Rong Lu, Santosh E Gummidipundi, Jordi Garcia-Diaz and 2 more

Open access · greenAbstract read
In one paragraph

Article in European journal of nuclear medicine and molecular imaging, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed, 2 pooled it
9.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 2 syntheses or guidelines pooled it, 77 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Image optimization for low-doseEJNMMI physics · 2026
    Article
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  9. Applications of Artificial Intelligence for Pediatric Cancer Imaging.AJR. American journal of roentgenology · 2024
    Review
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  18. Acquisition time reduction in pediatricJournal of applied clinical medical physics · 2023
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Yan-Ran Joyce Wang *Department of Radiology, Molecular Imaging Program at Stanford, Stanford University, 725 Welch Road, CA, 94304, Stanford, USA.
Lucia Baratto *Department of Radiology, Molecular Imaging Program at Stanford, Stanford University, 725 Welch Road, CA, 94304, Stanford, USA.
K Elizabeth HawkDepartment of Radiology, Molecular Imaging Program at Stanford, Stanford University, 725 Welch Road, CA, 94304, Stanford, USA.
Ashok J TheruvathDepartment of Radiology, Molecular Imaging Program at Stanford, Stanford University, 725 Welch Road, CA, 94304, Stanford, USA.
Allison PribnowDepartment of Pediatrics, Pediatric Oncology, Lucile Packard Children's Hospital, Stanford University, Stanford, CA, 94304, USA.
Avnesh S ThakorDepartment of Radiology, Molecular Imaging Program at Stanford, Stanford University, 725 Welch Road, CA, 94304, Stanford, USA.
Sergios GatidisDepartment of Diagnostic and Interventional Radiology, University Hospital Tuebingen, Tuebingen, Germany.
Rong LuQuantitative Sciences Unit, School of Medicine, Stanford University, Stanford, CA, 94304, USA.
Santosh E GummidipundiQuantitative Sciences Unit, School of Medicine, Stanford University, Stanford, CA, 94304, USA.
Jordi Garcia-DiazDepartment of Radiology, Molecular Imaging Program at Stanford, Stanford University, 725 Welch Road, CA, 94304, Stanford, USA.
Daniel RubinDepartment of Radiology, Molecular Imaging Program at Stanford, Stanford University, 725 Welch Road, CA, 94304, Stanford, USA. drubin@stanford.edu.
Heike E Daldrup-LinkDepartment of Radiology, Molecular Imaging Program at Stanford, Stanford University, 725 Welch Road, CA, 94304, Stanford, USA. heiked@stanford.edu.ORCID http://orcid.org/0000-0002-4929-819X
Stanford University · USLucile Packard Children's Hospital · US

Funding

Translational Oncology Research Program (Project-005)P30CA124435 · NCI · STANFORD UNIVERSITY · PI Melinda L. Telli · 2007 to 2026
$71.4M
Personalized Whole Body Staging for Children with Cancer: A Solution to the Conundrum of Long-Term Side Effects from CT and PET/CT ScansR01HD081123 · NICHD · STANFORD UNIVERSITY · PI DALDRUP-LINK, HEIKE ELIZABETH · 2015 to 2019
$2.5M
NCI NIH HHS P30 CA124435NICHD NIH HHS R01 HD081123
6 · The paper itself

Abstract

purposeTo generate diagnostic

methodsWe used whole-body

resultsThe peak signal-to-noise ratio and structural similarity index were significantly higher, and the normalized root-mean-square error was significantly lower on the AI-reconstructed PET images compared to simulated 6.25% dose images (p < 0.001). Compared to the ground-truth standard-dose PET, SUV

conclusionsOur CNN model could generate simulated clinical standard

Indexed as

Artificial IntelligenceRadiation ExposureChildFluorodeoxyglucose F18HumansMagnetic Resonance ImagingPositron-Emission TomographyWhole Body ImagingYoung AdultFluorodeoxyglucose F18Deep learningPediatric cancer imagingPET denoisingPET/MRIWhole-body PET reconstruction

Identifiers

PMID33527176
PMCPMC8266729
OpenAlexW3126557061

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.