Evidence map›Paper›PMID 33527016›Full record

ArticleAmerican journal of translational research2021

Systematic analysis using a bioinformatics strategy identifies SFTA1P and LINC00519 as potential prognostic biomarkers for lung squamous cell carcinoma.

Yu-Zhen Yin, Shi-Hua Yao, Chun-Guang Li, Yu-Shui Ma, Zhou-Jun Kang, Jia-Jia Zhang, Cheng-You Jia, Li-Kun Hou, Shan-Shan Qin, Xin Fan and 17 more

Open access · greenAbstract read
In one paragraph

Article in American journal of translational research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.6field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

27 authors at 3 institutions in 1 country.

Yu-Zhen YinDepartment of Nuclear Medicine, Shanghai Tenth People's Hospital, Tongji University School of Medicine Shanghai 200072, China.
Shi-Hua YaoDepartment of Thoracic Surgery, Navy Military Medical University Affiliated Changhai Hospital Shanghai 200433, China.
Chun-Guang LiDepartment of Thoracic Surgery, Navy Military Medical University Affiliated Changhai Hospital Shanghai 200433, China.
Yu-Shui MaDepartment of Nuclear Medicine, Shanghai Tenth People's Hospital, Tongji University School of Medicine Shanghai 200072, China.
Zhou-Jun KangDepartment of Emergency, Navy Military Medical University Affiliated Changhai Hospital Shanghai 200433, China.
Jia-Jia ZhangDepartment of Nuclear Medicine, Shanghai Tenth People's Hospital, Tongji University School of Medicine Shanghai 200072, China.
Cheng-You JiaDepartment of Nuclear Medicine, Shanghai Tenth People's Hospital, Tongji University School of Medicine Shanghai 200072, China.
Li-Kun HouDepartment of Pathology, Shanghai Pulmonary Hospital, Tongji University School of Medicine Shanghai 200433, China.
Shan-Shan QinDepartment of Nuclear Medicine, Shanghai Tenth People's Hospital, Tongji University School of Medicine Shanghai 200072, China.
Xin FanDepartment of Nuclear Medicine, Shanghai Tenth People's Hospital, Tongji University School of Medicine Shanghai 200072, China.
Han ZhangDepartment of Nuclear Medicine, Shanghai Tenth People's Hospital, Tongji University School of Medicine Shanghai 200072, China.
Meng-Die YangDepartment of Nuclear Medicine, Shanghai Tenth People's Hospital, Tongji University School of Medicine Shanghai 200072, China.
Dan-Dan ZhangCentral Laboratory for Medical Research, Shanghai Tenth People's Hospital, Tongji University School of Medicine Shanghai 200072, China.
Gai-Xia LuDepartment of Nuclear Medicine, Shanghai Tenth People's Hospital, Tongji University School of Medicine Shanghai 200072, China.
Hui-Min WangCentral Laboratory for Medical Research, Shanghai Tenth People's Hospital, Tongji University School of Medicine Shanghai 200072, China.
Li-Peng GuCentral Laboratory for Medical Research, Shanghai Tenth People's Hospital, Tongji University School of Medicine Shanghai 200072, China.
Lin-Lin TianCentral Laboratory for Medical Research, Shanghai Tenth People's Hospital, Tongji University School of Medicine Shanghai 200072, China.
Pei-Yao WangCentral Laboratory for Medical Research, Shanghai Tenth People's Hospital, Tongji University School of Medicine Shanghai 200072, China.
Ping-Sheng CaoCentral Laboratory for Medical Research, Shanghai Tenth People's Hospital, Tongji University School of Medicine Shanghai 200072, China.
Wei WuDepartment of Pathology, Shanghai Pulmonary Hospital, Tongji University School of Medicine Shanghai 200433, China.
Zi-Yang CaoDepartment of Pathology, Shanghai Pulmonary Hospital, Tongji University School of Medicine Shanghai 200433, China.
Zhong-Wei LvDepartment of Nuclear Medicine, Shanghai Tenth People's Hospital, Tongji University School of Medicine Shanghai 200072, China.
Bo-Wen ShiDepartment of Thoracic Surgery, Navy Military Medical University Affiliated Changhai Hospital Shanghai 200433, China.
Chun-Yan WuDepartment of Pathology, Shanghai Pulmonary Hospital, Tongji University School of Medicine Shanghai 200433, China.
Geng-Xi JiangDepartment of Thoracic Surgery, Navy Military Medical University Affiliated Changhai Hospital Shanghai 200433, China.
Da FuCentral Laboratory for Medical Research, Shanghai Tenth People's Hospital, Tongji University School of Medicine Shanghai 200072, China.
Fei YuDepartment of Nuclear Medicine, Shanghai Tenth People's Hospital, Tongji University School of Medicine Shanghai 200072, China.
Tongji University · CNShanghai Tenth People's Hospital · CNShanghai Pulmonary Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lung cancer has high incidence and mortality rates, in which lung squamous cell carcinoma (LUSC) is a primary type of non-small cell lung carcinoma (NSCLC). The aim of our study was to discover long non-coding RNAs (lncRNAs) associated with diagnose and prognosis for LUSC. RNA sequencing data obtained from LUSC samples were extracted from The Cancer Genome Atlas database (TCGA). Two prognosis-associated lncRNAs (including SFTA1P and LINC00519) were selected from LUSC samples, and the expression levels were also verified to be associated abnormal in LUSC clinical samples. Our findings demonstrate that lncRNAs SFTA1P and LINC00519 exert important functions in human LUSC and may serve as new targets for LUSC diagnosis and therapy.

Indexed as

diagnosisLINC00519LUSCprognosisSFTA1P

Identifiers

PMID33527016
PMCPMC7847518
OpenAlexW3126566345

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.