Evidence map›Paper›PMID 33526972›Full record

ArticleInternational journal of medical sciences2021

Differences in detected safety signals between benzodiazepines and non-benzodiazepine hypnotics: pharmacovigilance study using a spontaneous reporting system.

Manabu Toyoshima, Yoshihiro Noguchi, Manami Otsubo, Tomoya Tachi, Hitomi Teramachi

Open access · goldAbstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of medical sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.5field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

  1. Dual orexin receptor antagonist-assisted dose reduction of benzodiazepines and benzodiazepine receptor agonists: a mirror-image analysis of insurance claims data.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Manabu ToyoshimaDepartment of Pharmacy, Kawasaki rinko general hospital; 3-13-1 Nakashima, Kawasaki-ku, Kawasaki, 210-0806, Kanagawa, Japan.
Yoshihiro NoguchiLaboratory of Clinical Pharmacy, Gifu Pharmaceutical University; 1-25-4, Daigakunishi, Gifu, 501-1196, Gifu, Japan.
Manami OtsuboDepartment of Pharmacy, Gifu University Hospital; 1-1, Yanagido, Gifu, 501-1194, Gifu, Japan.
Tomoya TachiLaboratory of Clinical Pharmacy, Gifu Pharmaceutical University; 1-25-4, Daigakunishi, Gifu, 501-1196, Gifu, Japan.
Hitomi TeramachiLaboratory of Clinical Pharmacy, Gifu Pharmaceutical University; 1-25-4, Daigakunishi, Gifu, 501-1196, Gifu, Japan.
Gifu Pharmaceutical University · JPGifu University Hospital · JPKawasaki Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Adverse Drug Reaction Reporting SystemsBenzodiazepinesDrug-Related Side Effects and Adverse ReactionsDrug SubstitutionHumansHypnotics and SedativesJapanPharmacovigilanceSleep Initiation and Maintenance DisordersBenzodiazepinesHypnotics and Sedativesbenzodiazepine-based hypnoticsJapanese Adverse Drug Event Report databasenon-benzodiazepine-based hypnoticssignal detection

Identifiers

PMID33526972
PMCPMC7847624
OpenAlexW3118307062

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.