Evidence map›Paper›PMID 33526864›Full record

ArticleThe Journal of antibiotics2021

Herbicidal bio-assay of isocladosporin enantiomers and determination of its plausible absolute configuration.

Yash Mankad, Pronay Das, Ejaj Pathan, M V Deshpande, D Srinivasa Reddy

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Article in The Journal of antibiotics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yash MankadDivision of Organic Chemistry, CSIR-National Chemical Laboratory, Dr. Homi Bhabha Road, Pune, 411008, India.
Pronay DasDivision of Organic Chemistry, CSIR-National Chemical Laboratory, Dr. Homi Bhabha Road, Pune, 411008, India.
Ejaj PathanAcademy of Scientific and Innovative Research (AcSIR), Ghaziabad, 201002, India.
M V DeshpandeAcademy of Scientific and Innovative Research (AcSIR), Ghaziabad, 201002, India. mv.deshpande@ncl.res.in.
D Srinivasa ReddyDivision of Organic Chemistry, CSIR-National Chemical Laboratory, Dr. Homi Bhabha Road, Pune, 411008, India. ds.reddy@ncl.res.in.ORCID http://orcid.org/0000-0003-3270-315X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A fungal metabolite, isocladosporin was isolated from natural fungus, Cladosporium cladosporioides in the mid of 90s. Due to the lack of optical rotation of isolated natural product sample, the absolute configuration of the natural product remained undetermined for more than two decades. Herein, we demonstrated an SAR study of enantiomers of isocladosporin in herbicidal bio-assay against wheat coleoptile. Using this study as a comparative tool we further proposed the plausible absolute configuration of natural isocladosporin for the first time. The assigned configuration was also supported through biogenetic precursors.

Indexed as

AnimalsCladosporiumColeopteraHerbicidesIsocoumarinsStereoisomerismStructure-Activity RelationshipTriticumcladosporinHerbicidesIsocoumarins

Identifiers

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.