Evidence map›Paper›PMID 33526716›Full record

ArticleJournal of cell science2021

Circulating prostate cancer cells have differential resistance to fluid shear stress-induced cell death.

Jacob M Hope, Matthew R Bersi, Jenna A Dombroski, Andrea B Clinch, Rebecca S Pereles, W David Merryman, Michael R King

Open access · hybridAbstract read
In one paragraph

Article in Journal of cell science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
2.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 37 citations in OpenAlex.

  1. Article
  2. Review
  3. Model Circulating Tumor Cells Induced by Mechanical Stress.Methods in molecular biology (Clifton, N.J.) · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Jacob M HopeDepartment of Biomedical Engineering, Vanderbilt University, 5824 Stevenson Center, Nashville, TN 37235, USA.
Matthew R BersiDepartment of Biomedical Engineering, Vanderbilt University, 5824 Stevenson Center, Nashville, TN 37235, USA.
Jenna A DombroskiDepartment of Biomedical Engineering, Vanderbilt University, 5824 Stevenson Center, Nashville, TN 37235, USA.
Andrea B ClinchDepartment of Biomedical Engineering, Vanderbilt University, 5824 Stevenson Center, Nashville, TN 37235, USA.
Rebecca S PerelesDepartment of Biomedical Engineering, Vanderbilt University, 5824 Stevenson Center, Nashville, TN 37235, USA.
W David MerrymanDepartment of Biomedical Engineering, Vanderbilt University, 5824 Stevenson Center, Nashville, TN 37235, USA.
Michael R KingDepartment of Biomedical Engineering, Vanderbilt University, 5824 Stevenson Center, Nashville, TN 37235, USA mike.king@vanderbilt.edu.ORCID 0000-0002-0223-7808
Vanderbilt University · US

Funding

Super Natural Killer Cells That Target Metastases in the Tumor-Draining Lymph NodesR01CA203991 · NCI · VANDERBILT UNIVERSITY · PI KING, MICHAEL R. · 2017 to 2021
$1.9M
NCI NIH HHS R01 CA203991
6 · The paper itself

Abstract

Circulating tumor cells (CTCs) are exposed to fluid shear stress (FSS) of greater than 1000 dyn/cm

Indexed as

Neoplastic Cells, CirculatingProstatic NeoplasmsCell DeathCell Line, TumorHumansMaleStress, MechanicalCancerMechanotransductionMembrane

Identifiers

PMID33526716
PMCPMC7929932
OpenAlexW3128704788

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.