Evidence map›Paper›PMID 33526714›Full record

ArticleJournal of cell science2021

Activation of meiotic recombination by nuclear import of the DNA break hotspot-determining complex in fission yeast.

Mélody Wintrebert, Mai-Chi Nguyen, Gerald R Smith

Open access · bronzeAbstract read
In one paragraph

Article in Journal of cell science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Mélody WintrebertDivision of Basic Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.
Mai-Chi NguyenDivision of Basic Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.
Gerald R SmithDivision of Basic Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA gsmith@fredhutch.org.ORCID 0000-0002-8747-1352
Fred Hutch Cancer Center · US

Funding

Molecular analysis of genetic recombination and DNA break repairR35GM118120 · NIGMS · FRED HUTCHINSON CANCER RESEARCH CENTER · PI SMITH, GERALD R · 2016 to 2025
$9.3M
NIGMS NIH HHS R35 GM118120
6 · The paper itself

Abstract

Meiotic recombination forms crossovers important for proper chromosome segregation and offspring viability. This complex process involves many proteins acting at each of the multiple steps of recombination. Recombination initiates by formation of DNA double-strand breaks (DSBs), which in the several species examined occur with high frequency at special sites (DSB hotspots). In

Indexed as

SchizosaccharomycesSchizosaccharomyces pombe ProteinsActive Transport, Cell NucleusCell Cycle ProteinsDNA Breaks, Double-StrandedMeiosisNuclear ProteinsCell Cycle ProteinsMug20 protein, S pombeNuclear ProteinsREC10 protein, S pombeRec25 protein, S pombeRec27 protein, S pombeSchizosaccharomyces pombe ProteinsDSB hotspot determinantsLinear element proteinsMeiotic recombinationNuclear localization signalS. pombeSynaptonemal complex proteins

Identifiers

PMID33526714
PMCPMC7929924
OpenAlexW3129087239

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.