Evidence map›Paper›PMID 33526664›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2021

Area-specific thalamocortical synchronization underlies the transition from motor planning to execution.

Abdulraheem Nashef, Rea Mitelman, Ran Harel, Mati Joshua, Yifat Prut

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 30 citations in OpenAlex.

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  6. Cross-Frequency Coupling as a Biomarker for Early Stroke Recovery.Neurorehabilitation and neural repair · 2024
    Article
  7. Modeling and dissociation of intrinsic and input-driven neural population dynamics underlying behavior.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
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  12. Functional near-infrared spectroscopy during motor imagery and motor execution in healthy adults.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Abdulraheem NashefDepartment of Medical Neurobiology, Hadassah Medical School, The Hebrew University, 9112102 Jerusalem, Israel.ORCID 0000-0003-4308-3355
Rea MitelmanDepartment of Medical Neurobiology, Hadassah Medical School, The Hebrew University, 9112102 Jerusalem, Israel.ORCID 0000-0003-1271-7757
Ran HarelDepartment of Neurosurgery, Sheba Medical Center, 5262000 Tel Aviv, Israel.ORCID 0000-0002-0165-7114
Mati JoshuaThe Edmond and Lily Safra Center for Brain Sciences, The Hebrew University, 9190401 Jerusalem, Israel.
Yifat PrutDepartment of Medical Neurobiology, Hadassah Medical School, The Hebrew University, 9112102 Jerusalem, Israel; yifat.prut@mail.huji.ac.il.ORCID 0000-0003-1988-8794
Sheba Medical Center · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We studied correlated firing between motor thalamic and cortical cells in monkeys performing a delayed-response reaching task. Simultaneous recording of thalamocortical activity revealed that around movement onset, thalamic cells were positively correlated with cell activity in the primary motor cortex but negatively correlated with the activity of the premotor cortex. The differences in the correlation contrasted with the average neural responses, which were similar in all three areas. Neuronal correlations reveal functional cooperation and opposition between the motor thalamus and distinct motor cortical areas with specific roles in planning vs. performing movements. Thus, by enhancing and suppressing motor and premotor firing, the motor thalamus can facilitate the transition from a motor plan to execution.

Indexed as

AnimalsCortical SynchronizationFemaleMacaca fascicularisMotor ActivityMotor CortexNeuronsTask Performance and AnalysisThalamuscerebellummotor cortexmotor thalamusmovement initiationnonhuman primates

Identifiers

PMID33526664
PMCPMC8017695
OpenAlexW3128227988

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.