Evidence map›Paper›PMID 33526658›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2021

Cell dispersal by localized degradation of a chemoattractant.

Richa Karmakar, Timothy Tyree, Richard H Gomer, Wouter-Jan Rappel

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Many Cells Make Light Work: Self-Generated Gradients OrganizeCold Spring Harbor perspectives in biology · 2026
    Review
  2. Article
  3. Pattern formation along signaling gradients driven by active droplet behavior of cell swarms.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Richa KarmakarDepartment of Physics, University of California San Diego, La Jolla, CA 92093.ORCID 0000-0002-9741-6816
Timothy TyreeDepartment of Physics, University of California San Diego, La Jolla, CA 92093.ORCID 0000-0003-0897-5083
Richard H GomerDepartment of Biology, Texas A&M University, College Station, TX 77843.ORCID 0000-0003-2361-4307
Wouter-Jan RappelDepartment of Physics, University of California San Diego, La Jolla, CA 92093; rappel@physics.ucsd.edu.ORCID 0000-0003-3833-7197
University of California San Diego · USTexas A&M University · US

Funding

Elucidation of a Eukaryotic Chemorepulsion MechanismR35GM139486 · NIGMS · TEXAS A&M UNIVERSITY · PI Richard H Gomer · 2021 to 2026
$2.3M
Training Program in Quantitative Integrative BiologyT32GM127235 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI HWA, TERENCE · 2018 to 2022
$1.3M
Elucidation of a eukaryotic chemorepulsion mechanismR01GM118355 · NIGMS · TEXAS A&M UNIVERSITY · PI GOMER, RICHARD H · 2016 to 2019
$1.2M
NIGMS NIH HHS R01 GM118355NIGMS NIH HHS R35 GM139486NIGMS NIH HHS T32 GM127235
6 · The paper itself

Abstract

Chemotaxis, the guided motion of cells by chemical gradients, plays a crucial role in many biological processes. In the social amoeba

Indexed as

Cell MovementCell AggregationChemotactic FactorsComputer SimulationCyclic AMPDictyosteliumFluorescencePhosphodiesterase InhibitorsPhosphoric Diester HydrolasesSignal TransductionChemotactic FactorsCyclic AMPPhosphodiesterase InhibitorsPhosphoric Diester HydrolaseschemotaxisDictyostelium discoideumdispersalrepulsion

Identifiers

PMID33526658
PMCPMC8017704
OpenAlexW3127018496

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.