Evidence map›Paper›PMID 33526612›Full record

ArticleJournal of bacteriology2021

Holin-Dependent Secretion of the Large Clostridial Toxin TpeL by Clostridium perfringens.

Angela Saadat, Stephen B Melville

Open access · greenAbstract read
In one paragraph

Article in Journal of bacteriology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. iScience · 2025
    Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Review
  10. Article
  11. Review
  12. Article
  13. Article
  14. Large Clostridial Toxins: Mechanisms and Roles in Disease.Microbiology and molecular biology reviews : MMBR · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Angela SaadatDepartment of Biological Sciences, Virginia Tech, Blacksburg, Virginia, USA.
Stephen B MelvilleDepartment of Biological Sciences, Virginia Tech, Blacksburg, Virginia, USA melville@vt.edu.ORCID 0000-0002-0116-4280
Virginia Tech · US

Funding

Characterization of a Type II secretion system in a Gram-positive pathogenR21AI109391 · NIAID · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI MELVILLE, STEPHEN · 2014 to 2015
$413k
NIAID NIH HHS R21 AI109391
6 · The paper itself

Abstract

Large clostridial toxins (LCTs) are secreted virulence factors found in several species, including

Indexed as

Bacterial ProteinsBacterial Secretion SystemsBacterial ToxinsClostridium perfringensGene Expression Regulation, BacterialProtein TransportBacterial ProteinsBacterial Secretion SystemsBacterial ToxinsClostridiummolecular geneticsperfringenssecretion systemstoxin

Identifiers

PMID33526612
PMCPMC8088506
OpenAlexW3129183686

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.