Evidence map›Paper›PMID 33526120›Full record

ArticleJournal of cannabis research2020

Overbaked: assessing and predicting acute adverse reactions to Cannabis.

Emily M LaFrance, Amanda Stueber, Nicholas C Glodosky, Dakota Mauzay, Carrie Cuttler

Open access · goldAbstract read
In one paragraph

Article in Journal of cannabis research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 35 citations in OpenAlex.

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  3. Endocannabinoid signaling in stress, nausea, and vomiting.Neurogastroenterology and motility · 2025
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  9. Self-reported adverse events associated with ∆Journal of cannabis research · 2023
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  14. Medical Cannabis for Headache Pain: a Primer for Clinicians.Current pain and headache reports · 2021
    Review
  15. Article
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  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Emily M LaFranceDepartment of Psychology, Washington State University, P.O. Box 644820, Pullman, WA, 99164-4820, USA. emily.lafrance@wsu.edu.ORCID http://orcid.org/0000-0002-5198-5722
Amanda StueberDepartment of Psychology, Washington State University, P.O. Box 644820, Pullman, WA, 99164-4820, USA.
Nicholas C GlodoskyDepartment of Psychology, Washington State University, P.O. Box 644820, Pullman, WA, 99164-4820, USA.
Dakota MauzayDepartment of Psychology, Washington State University, P.O. Box 644820, Pullman, WA, 99164-4820, USA.
Carrie CuttlerDepartment of Psychology, Washington State University, P.O. Box 644820, Pullman, WA, 99164-4820, USA.
Washington State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTrends toward legalizing cannabis may increase experimentation with the drug among less experienced users with limited knowledge of possible adverse reactions. This study explores the prevalence, frequency, and levels of distress produced by various acute adverse reactions to cannabis, as well as predictors of these reactions.

methodsThe Adverse Reactions Scale (ARS) was created and administered to a large sample of undergraduate college students (n = 999) who were predominantly white (> 70%), female (> 70%), recreational (> 90%) cannabis users. The ARS was administered in an anonymous online survey measuring demographics, cannabis use patterns, cannabis use motives, personality, and negative affect.

resultsThe most prevalent adverse reactions to cannabis were coughing fits, anxiety, and paranoia, which > 50% of the sample reported experiencing. The most frequently occurring reactions were coughing fits, chest/lung discomfort, and body humming, which occurred on approximately 30-40% of cannabis use sessions. Panic attacks, fainting, and vomiting were rated as the most distressing, with mean ratings falling between "moderately" and "quite" distressing. Multiple regression analyses revealed that lower frequency of cannabis use predicted increased frequency of adverse reactions. Symptoms of cannabis use disorder, conformity motives, and anxiety sensitivity were significant predictors of both the prevalence of, and distress caused by, adverse reactions.

conclusionsRelative to past research, this study provides a more comprehensive account of possible adverse reactions to cannabis, and individual difference variables that predict these reactions. This study has implications for inexperienced cannabis users, as well as medical professionals and budtenders who provide information about cannabis use.

Indexed as

Adverse reactionsAnxietyCannabis useParanoiaSide effects

Identifiers

PMID33526120
PMCPMC7819287
OpenAlexW3031615801

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.