Evidence map›Paper›PMID 33525893›Full record

ArticleCirculation. Heart failure2021

Better Understanding the Disparity Associated With Black Race in Heart Transplant Outcomes: A National Registry Analysis.

Hasina Maredia, Mary Grace Bowring, Allan B Massie, Sunjae Bae, Amber Kernodle, Shakirat Oyetunji, Christian Merlo, Robert S D Higgins, Dorry L Segev, Errol L Bush

Open access · bronzeAbstract read
In one paragraph

Article in Circulation. Heart failure, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
8.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 46 citations in OpenAlex.

  1. Article
  2. Unequal Hearts: Racial Disparities Persist in Heart Transplant Outcomes.Journal of the American Heart Association · 2025
    Article
  3. Article
  4. Article
  5. Review
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  7. Article
  8. Article
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  11. Article
  12. Are There Racial Disparities in Perioperative Pain? A Retrospective Study of a Gynecological Surgery Cohort.Journal of perianesthesia nursing : official journal of the American Society of PeriAnesthesia Nurses · 2024
    Article
  13. Investigating health disparities in vestibular rehabilitation.Journal of vestibular research : equilibrium & orientation · 2024
    Article
  14. Article
  15. Article
  16. Review
  17. Racial disparity exists in the utilization and post-transplant survival benefit of ventricular assist device support in children.The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · 2023
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Hasina MarediaDepartment of Surgery (H.M., M.G.B., A.B.M., S.B., A.K., S.O., R.S.D.H., D.L.S., E.L.B.), Johns Hopkins University School of Medicine, Baltimore, MD.
Mary Grace BowringDepartment of Surgery (H.M., M.G.B., A.B.M., S.B., A.K., S.O., R.S.D.H., D.L.S., E.L.B.), Johns Hopkins University School of Medicine, Baltimore, MD.
Allan B MassieDepartment of Surgery (H.M., M.G.B., A.B.M., S.B., A.K., S.O., R.S.D.H., D.L.S., E.L.B.), Johns Hopkins University School of Medicine, Baltimore, MD.
Sunjae BaeDepartment of Surgery (H.M., M.G.B., A.B.M., S.B., A.K., S.O., R.S.D.H., D.L.S., E.L.B.), Johns Hopkins University School of Medicine, Baltimore, MD.
Amber KernodleDepartment of Surgery (H.M., M.G.B., A.B.M., S.B., A.K., S.O., R.S.D.H., D.L.S., E.L.B.), Johns Hopkins University School of Medicine, Baltimore, MD.
Shakirat OyetunjiDepartment of Surgery (H.M., M.G.B., A.B.M., S.B., A.K., S.O., R.S.D.H., D.L.S., E.L.B.), Johns Hopkins University School of Medicine, Baltimore, MD.
Christian MerloDepartment of Medicine (C.M.), Johns Hopkins University School of Medicine, Baltimore, MD.
Robert S D HigginsDepartment of Surgery (H.M., M.G.B., A.B.M., S.B., A.K., S.O., R.S.D.H., D.L.S., E.L.B.), Johns Hopkins University School of Medicine, Baltimore, MD.
Dorry L SegevDepartment of Surgery (H.M., M.G.B., A.B.M., S.B., A.K., S.O., R.S.D.H., D.L.S., E.L.B.), Johns Hopkins University School of Medicine, Baltimore, MD.
Errol L BushDepartment of Surgery (H.M., M.G.B., A.B.M., S.B., A.K., S.O., R.S.D.H., D.L.S., E.L.B.), Johns Hopkins University School of Medicine, Baltimore, MD.
Johns Hopkins University · USBloomberg (United States) · US

Funding

Medical Scientist Training ProgramT32GM136577 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI ANDREA L COX · 2020 to 2026
$13.4M
Patient Oriented Research in Solid Organ TransplantationK24AI144954 · NIAID · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI SEGEV, DORRY L. · 2020 to 2024
$956k
Patient Oriented Research in Kidney Disease and Transplant SurgeryK24DK101828 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI SEGEV, DORRY L. · 2014 to 2018
$922k
Determinants of chronic kidney disease in African-American live kidney donorsK01DK101677 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI MASSIE, ALLAN B · 2015 to 2019
$789k
NIAID NIH HHS K24 AI144954NIDDK NIH HHS K01 DK101677NIDDK NIH HHS K24 DK101828NIGMS NIH HHS T32 GM136577
6 · The paper itself

Abstract

backgroundBlack heart transplant recipients have higher risk of mortality than White recipients. Better understanding of this disparity, including subgroups most affected and timing of the highest risk, is necessary to improve care of Black recipients. We hypothesize that this disparity may be most pronounced among young recipients, as barriers to care like socioeconomic factors may be particularly salient in a younger population and lead to higher early risk of mortality.

methodsWe studied 22 997 adult heart transplant recipients using the Scientific Registry of Transplant Recipients data from January 2005 to 2017 using Cox regression models adjusted for recipient, donor, and transplant characteristics.

resultsAmong recipients aged 18 to 30 years, Black recipients had 2.05-fold (95% CI, 1.67-2.51) higher risk of mortality compared with non-Black recipients (

conclusionsYoung Black recipients have a high risk of mortality in the first year after heart transplant, which has been masked in decades of research looking at disparities in aggregate. To reduce overall racial disparities, clinical research moving forward should focus on targeted interventions for young Black recipients during this period.

Indexed as

Black or African AmericanHeart TransplantationMortalityAdolescentAdultAgedAged, 80 and overAge FactorsAmerican Indian or Alaska NativeAntilymphocyte SerumCardiomyopathiesCause of DeathDiabetes MellitusEducational StatusFemaleGlucocorticoidsAntilymphocyte SerumGlucocorticoidsImmunosuppressive AgentsInterleukin-2Mycophenolic AcidTacrolimusthymoglobulinadultagedepidemiologytissue donorstransplants

Identifiers

PMID33525893
PMCPMC7887117
OpenAlexW3128414531

What OpenQuestion holds

Textmetadata
LicenceTDM
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.