Evidence map›Paper›PMID 33525659›Full record

ArticleInternational journal of molecular sciences2021

ELOVL5 Participates in Embryonic Lipid Determination of Cellular Membranes and Cytoplasmic Droplets.

Franciele Lanzarini, Fernanda Alves Pereira, Janine de Camargo, Andressa Minozzo Oliveira, Katia Roberta Anacleto Belaz, Jose Javier Melendez-Perez, Marcos Nogueira Eberlin, Mário Celso Sperotto Brum, Fernando Silveira Mesquita, Mateus José Sudano

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Franciele LanzariniCurso de Medicina Veterinária, Universidade Federal do Pampa, Unipampa, Uruguaiana 96460-000, RS, Brazil.
Fernanda Alves PereiraCurso de Medicina Veterinária, Universidade Federal do Pampa, Unipampa, Uruguaiana 96460-000, RS, Brazil.
Janine de CamargoCurso de Medicina Veterinária, Universidade Federal do Pampa, Unipampa, Uruguaiana 96460-000, RS, Brazil.
Andressa Minozzo OliveiraCurso de Medicina Veterinária, Universidade Federal do Pampa, Unipampa, Uruguaiana 96460-000, RS, Brazil.
Katia Roberta Anacleto BelazInstituto de Química, Universidade Federal de Catalão, UFG/UFCAT, Catalão 75705-220, GO, Brazil.ORCID 0000-0003-0626-1992
Jose Javier Melendez-PerezUnidade Integrada de Farmacologia e Gastroenterologia, Bragança Paulista 12916-900, SP, Brazil.
Marcos Nogueira EberlinNúcleo de Pesquisa do Mackenzie em Ciência, Fé e Sociedade, Universidade Presbiteriana Mackenzie, São Paulo 01302-907, SP, Brazil.
Mário Celso Sperotto BrumCurso de Medicina Veterinária, Universidade Federal do Pampa, Unipampa, Uruguaiana 96460-000, RS, Brazil.ORCID 0000-0002-1643-1126
Fernando Silveira MesquitaCurso de Medicina Veterinária, Universidade Federal do Pampa, Unipampa, Uruguaiana 96460-000, RS, Brazil.ORCID 0000-0002-4433-0832
Mateus José SudanoCurso de Medicina Veterinária, Universidade Federal do Pampa, Unipampa, Uruguaiana 96460-000, RS, Brazil.ORCID 0000-0002-7699-4449
Universidade Federal do Pampa · BRUniversidade Federal de São Carlos · BRUnidade Integrada de Farmacologia e Gastroenterologia · BRUniversidade Estadual de Campinas (UNICAMP) · BRUniversidade Presbiteriana Mackenzie · BR

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico 446647/2014-4Coordenação de Aperfeiçoamento de Pessoal de Nível Superior financial code 1Foundation for Research Support of the State of Rio Grande do Sul scholarshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) 2012/07206-0
6 · The paper itself

Abstract

Embryonic lipids are crucial for the formation of cellular membranes and dynamically participate in metabolic pathways. Cells can synthesize simple fatty acids, and the elongation of fatty acids facilitates the formation of complex lipids. The aim of this work was to investigate the involvement of the elongation of very long chain fatty acid enzyme 5 (ELOVL5) in embryonic development and lipid determination. Bovine embryos were produced in vitro using a standard protocol and randomly divided to receive one of three treatments at Day 4: morpholino (Mo) gene expression knockdown assay for ELOVL5 (

Indexed as

Animalsbeta-GlobinsBlastocystCattleCell MembraneCytoplasmEmbryonic DevelopmentFatty Acid ElongasesFemaleGene Knockdown TechniquesHumansLipid MetabolismMorpholinosPregnancybeta-GlobinsFatty Acid ElongasesMorpholinosblastocystbovinecytoplasmic lipid depositearly embryo developmentfatty acid elongationlipid fingerprint

Identifiers

PMID33525659
PMCPMC7865478
OpenAlexW3125852875

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.