Evidence map›Paper›PMID 33525595›Full record

ReviewInternational journal of molecular sciences2021

The rDNA Loci-Intersections of Replication, Transcription, and Repair Pathways.

Ivana Goffová, Jiří Fajkus

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 42 citations in OpenAlex.

  1. Article
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  3. Review
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  7. Fish mapping of rdna and novel tandem repeats inComparative cytogenetics · 2026
    Article
  8. Article
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  11. Impacts of ribosomal RNA sequence variation on gene expression and phenotype.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2025
    Review
  12. Article
  13. Article
  14. Review
  15. Review
  16. Review
  17. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Ivana GoffováLaboratory of Functional Genomics and Proteomics, National Centre for Biomolecular Research, Faculty of Science, Masaryk University, CZ-61137 Brno, Czech Republic.ORCID 0000-0003-3977-8090
Jiří FajkusLaboratory of Functional Genomics and Proteomics, National Centre for Biomolecular Research, Faculty of Science, Masaryk University, CZ-61137 Brno, Czech Republic.ORCID 0000-0002-3112-1716
Central European Institute of Technology · CZ

Funding

European Regional Development Fund SYMBIT CZ.02.1.01/0.0/0.0/15_003/0000477Ministerstvo Školství, Mládeže a Tělovýchovy LTC20003
6 · The paper itself

Abstract

Genes encoding ribosomal RNA (rDNA) are essential for cell survival and are particularly sensitive to factors leading to genomic instability. Their repetitive character makes them prone to inappropriate recombinational events arising from collision of transcriptional and replication machineries, resulting in unstable rDNA copy numbers. In this review, we summarize current knowledge on the structure and organization of rDNA, its role in sensing changes in the genome, and its linkage to aging. We also review recent findings on the main factors involved in chromatin assembly and DNA repair in the maintenance of rDNA stability in the model plants

Indexed as

DNA RepairAgingAnimalsArabidopsisBryopsidaChromatin Assembly and DisassemblyDNA, PlantDNA ReplicationDNA, RibosomalGene DosageGenomic InstabilityHumansTranscription, GeneticDNA, PlantDNA, RibosomalCAF-1genome stabilityRAD51rDNA organizationribosomerRNA genesRTEL1

Identifiers

PMID33525595
PMCPMC7865372
OpenAlexW3124857304

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.