ArticleInternational journal of molecular sciences2021
Understanding the Effects of Anesthesia on Cortical Electrophysiological Recordings: A Scoping Review.
Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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Who cites it
30 citing papers in PubMed.
- Zwitterionic Polymer Coating Enabled Chronic Dopamine Sensing and Electrophysiology Recording in Free-Moving Mice.Advanced healthcare materials · 2026Article
- Homozygous CHD8 mutation intensifies ASD phenotypes and attenuates sex differences.Molecular psychiatry · 2026Article
- Whisker stimulation reinforces a resting-state network in the barrel cortex: Nested oscillations and avalanches.PLoS computational biology · 2026Article
- Early-life stress impairs development of functional interactions and neuronal activity within prefrontal-amygdala networks in vivo.Molecular psychiatry · 2026Article
- Tumor-Bearing Status Accelerates Bleomycin-Induced Pulmonary Inflammation via Endothelial Activation.Thoracic cancer · 2026Article
- Zwitterionic polymer coating enabled chronic dopamine sensing and electrophysiology recording in free-moving mice.bioRxiv : the preprint server for biology · 2026Article
- Alpha-synuclein overexpression reduces neural activity within a basal ganglia vocal nucleus in a zebra finch model.PloS one · 2026Article
- Ionic Direct Current Enables Millimeter- and Millisecond-Scale Cortical Gain Control in vivo.bioRxiv : the preprint server for biology · 2025Article
- The Glymphatic-Venous Axis in Brain Clearance Failure: Aquaporin-4 Dysfunction, Biomarker Imaging, and Precision Therapeutic Frontiers.International journal of molecular sciences · 2025Review
- PKC-dependent enhancement of glutamate input to VTA dopamine neurons in 3xTg-AD mice.bioRxiv : the preprint server for biology · 2025Article
- Anesthesiology Safety in Morocco: A Synthesis of Three Studies Towards Integrated Multidisciplinary Collaboration.Cureus · 2025Review
- In vivo microelectrode arrays for neuroscience.Nature reviews. Methods primers · 2025Article
- Multi-channel microelectrode arrays for detection of single-cell level neural information in the hippocampus CA1 under general anesthesia induced by low-dose isoflurane.Fundamental research · 2025Article
- Hemodynamic and neuronal contributions to low-frequency vascular oscillations in a preclinical model of Alzheimer's disease.Neurophotonics · 2025Article
- A high-density multi-electrode platform examining the effects of radiation on in vitro cortical networks.Scientific reports · 2024Article
- Exploring the Role of Ketamine Sedation in Critically Ill Patients: A Comprehensive Review.Cureus · 2024Review
- Flexible circumferential bioelectronics to enable 360-degree recording and stimulation of the spinal cord.Science advances · 2024Article
- Anesthetized animal experiments for neuroscience research.Frontiers in neural circuits · 2024Review
- Multi-finger receptive field properties in primary somatosensory cortex: A revised account of the spatiotemporal integration functions of area 3b.Cell reports · 2023Article
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
General anesthesia in animal experiments is an ethical must and is required for all the procedures that are likely to cause more than slight or momentary pain. As anesthetics are known to deeply affect experimental findings, including electrophysiological recordings of brain activity, understanding their mechanism of action is of paramount importance. It is widely recognized that the depth and type of anesthesia introduce significant bias in electrophysiological measurements by affecting the shape of both spontaneous and evoked signals, e.g., modifying their latency and relative amplitude. Therefore, for a given experimental protocol, it is relevant to identify the appropriate anesthetic, to minimize the impact on neuronal circuits and related signals under investigation. This review focuses on the effect of different anesthetics on cortical electrical recordings, examining their molecular mechanisms of action, their influence on neuronal microcircuits and, consequently, their impact on cortical measurements.
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