Evidence map›Paper›PMID 33525468›Full record

ArticlePathogens (Basel, Switzerland)2021

The Relevance of IL-1-Signaling in the Protection against Gram-Positive Bacteria.

Angelina Midiri, Giuseppe Mancuso, Concetta Beninati, Elisabetta Gerace, Carmelo Biondo

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pathogens (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Review
  3. New Insights into Bacterial Pathogenesis.Pathogens (Basel, Switzerland) · 2022
    Article
  4. Article
  5. Gasdermin D protects againstFrontiers in immunology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Angelina MidiriDepartment of Human Pathology, University of Messina, 90026 Messina, Italy.
Giuseppe MancusoDepartment of Human Pathology, University of Messina, 90026 Messina, Italy.
Concetta BeninatiDepartment of Human Pathology, University of Messina, 90026 Messina, Italy.ORCID 0000-0001-8305-1337
Elisabetta GeraceDepartment of Human Pathology, University of Messina, 90026 Messina, Italy.
Carmelo BiondoDepartment of Human Pathology, University of Messina, 90026 Messina, Italy.
University of Messina · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Previous studies performed using a model of group B streptococcus (GBS)-induced peritoneal inflammation indicate that the interleukin-1 receptor (IL-1R) family plays an important role in the innate host defense against this encapsulated Gram-positive bacteria. Since the role of IL-1-dependent signaling in peritoneal infections induced by other Gram-positive bacteria is unknown, in the present study we sought to investigate the contribution of IL-1R signaling in host defenses against

Indexed as

bacterial peritonitis modelsIL-1R signalinginflammatory chemokinesneutrophil recruitment

Identifiers

PMID33525468
PMCPMC7911888
OpenAlexW3123026252

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.