Evidence map›Paper›PMID 33525454›Full record

Observational studyNutrients2021

Visceral Adiposity Index (VAI) in Children and Adolescents with Obesity: No Association with Daily Energy Intake but Promising Tool to Identify Metabolic Syndrome (MetS).

Sara Vizzuso, Alberico Del Torto, Dario Dilillo, Valeria Calcaterra, Elisabetta Di Profio, Alessandro Leone, Luisa Gilardini, Simona Bertoli, Alberto Battezzati, Gian Vincenzo Zuccotti and 1 more

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed, 1 pooled it
11.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 1 synthesis or guideline pooled it, 75 citations in OpenAlex.

  1. Pooled it
  2. [Association between anthropometric clinical predictors and HOMA-IR].Revista medica del Instituto Mexicano del Seguro Social · 2026
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  9. Associations Between Dietary Diversity Score and Adiposity Indexes in Obese AdolescentsJournal of clinical research in pediatric endocrinology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Sara VizzusoDepartment of Pediatrics, Vittore Buzzi Children's Hospital, University of Milan, 20154 Milan, Italy.ORCID 0000-0002-3001-0387
Alberico Del TortoCentro Cardiologico Monzino IRCCS, 20138 Milan, Italy.ORCID 0000-0001-5074-2078
Dario DililloDepartment of Pediatrics, Vittore Buzzi Children's Hospital, University of Milan, 20154 Milan, Italy.
Valeria CalcaterraDepartment of Pediatrics, Vittore Buzzi Children's Hospital, University of Milan, 20154 Milan, Italy.ORCID 0000-0002-2137-5974
Elisabetta Di ProfioScience Nutrition, University of Milan, 20154 Milan, Italy.
Alessandro LeoneInternational Center for the Assessment of Nutritional Status (ICANS), Department of Food, Environmental and Nutritional Sciences (DeFENS), University of Milan, Via Sandro Botticelli 21, 20133 Milan, Italy.ORCID 0000-0001-8063-8490
Luisa GilardiniIstituto Auxologico Italiano, IRCCS, Lab of Nutrition and Obesity Research, 20145 Milan, Italy.
Simona BertoliInternational Center for the Assessment of Nutritional Status (ICANS), Department of Food, Environmental and Nutritional Sciences (DeFENS), University of Milan, Via Sandro Botticelli 21, 20133 Milan, Italy.ORCID 0000-0001-5867-8074
Alberto BattezzatiInternational Center for the Assessment of Nutritional Status (ICANS), Department of Food, Environmental and Nutritional Sciences (DeFENS), University of Milan, Via Sandro Botticelli 21, 20133 Milan, Italy.
Gian Vincenzo ZuccottiDepartment of Pediatrics, Vittore Buzzi Children's Hospital, University of Milan, 20154 Milan, Italy.ORCID 0000-0002-2795-9874
Elvira VerduciDepartment of Pediatrics, Vittore Buzzi Children's Hospital, University of Milan, 20154 Milan, Italy.ORCID 0000-0003-2111-3111
University of Milan · ITCentro Cardiologico Monzino · ITIRCCS Istituto Auxologico Italiano · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

(1) Background. Visceral adiposity index (VAI) has been recently identified as a new cardiometabolic risk marker reflecting abdominal fat distribution and dyslipidaemia. The aim of the present paper was to evaluate the relationship between VAI, daily energy intake and metabolic syndrome (MetS) in a cohort of obese Caucasian children and adolescents, aged 8 to 15 years. (2) Methods. Consecutive Italian children and adolescents with obesity, according to World Health Organization were enrolled. Anthropometric parameters and blood pressure were measured. Fasting blood samples have been analyzed for lipids, insulin and glucose levels. MetS was diagnosed using identification and prevention of dietary- and lifestyle-induced health effects in children and infants (IDEFICS) or International Diabetes Federation (IDF) criteria according to age. Homeostatic model assessment index (HOMA-IR), quantitative insulin sensitivity check index (QUICKI), A body shape index (ABSI) and VAI were calculated. Multivariable logistic regression analyses with sex, age and each anthropometric parameter (body mass index (BMI) z-score, ABSI, waist-to-height ratio (WHR)) or VAI was performed to predict MetS. Receiver operation curve (ROC) analysis was used to define the optimal VAI cut-off to identify MetS. Multiple regression was performed to predict the BMI z-score and VAI from daily energy intake after adjusting for age and sex. (3) Results. Six hundred and thirty-seven (313 boys and 324 girls) children and adolescents with obesity with median age 11 (interquartile range 10-13) years were included in the analysis. MetS was diagnosed in 79 patients. VAI correlated with BMI, WHR, ABSI, HOMA-IR, QUICKI, systolic blood pressure, low- and high-density lipoprotein cholesterol, triglycerides and triglycerides-to-HDL ratio (

Indexed as

AdiposityEnergy IntakeAdolescentBody Mass IndexChildFemaleHumansIntra-Abdominal FatLogistic ModelsMaleMetabolic SyndromeObesity, AbdominalROC Curvemetabolic syndromepediatric obesityvisceral adiposity index

Identifiers

PMID33525454
PMCPMC7911630
OpenAlexW3123493549

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.