Evidence map›Paper›PMID 33525395›Full record

ArticleGenes2021

Cdx2 Regulates Intestinal EphrinB1 through the Notch Pathway.

Yalun Zhu, Alexa Hryniuk, Tanya Foley, Bradley Hess, David Lohnes

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Genes, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. The EPH/Ephrin System in Colorectal Cancer.International journal of molecular sciences · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Yalun ZhuDepartment of Cellular and Molecular Medicine, University of Ottawa, 451 Smyth Road, Ottawa, ON K1H 8M5, Canada.
Alexa HryniukDepartment of Cellular and Molecular Medicine, University of Ottawa, 451 Smyth Road, Ottawa, ON K1H 8M5, Canada.
Tanya FoleyDepartment of Cellular and Molecular Medicine, University of Ottawa, 451 Smyth Road, Ottawa, ON K1H 8M5, Canada.
Bradley HessDepartment of Cellular and Molecular Medicine, University of Ottawa, 451 Smyth Road, Ottawa, ON K1H 8M5, Canada.
David LohnesDepartment of Cellular and Molecular Medicine, University of Ottawa, 451 Smyth Road, Ottawa, ON K1H 8M5, Canada.
University of Ottawa · CA

Funding

CIHR 148524
6 · The paper itself

Abstract

The majority of colorectal cancers harbor loss-of-function mutations in

Indexed as

Gene Expression RegulationSignal TransductionBiomarkersCDX2 Transcription FactorCell Line, TumorEphrin-B1HumansIntestinal MucosaModels, BiologicalPromoter Regions, GeneticReceptors, NotchBiomarkersCDX2 protein, humanCDX2 Transcription FactorEphrin-B1Receptors, NotchCdxcolorectal cancerdifferentiationEphrinB1NotchSW480

Identifiers

PMID33525395
PMCPMC7911442
OpenAlexW3121238326

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.