Evidence map›Paper›PMID 33525364›Full record

ReviewNanomaterials (Basel, Switzerland)2021

Physical Enhancement? Nanocarrier? Current Progress in Transdermal Drug Delivery.

Noriyuki Uchida, Masayoshi Yanagi, Hiroki Hamada

Abstract readReview
In one paragraph

Review in Nanomaterials (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Review
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  6. Review
  7. Article
  8. Article
  9. Nanomaterials in Drug Delivery Applications.Nanomaterials (Basel, Switzerland) · 2022
    Article
  10. Article
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  12. Article
  13. Review
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  15. Article
  16. Review
  17. Roles of Lipids in the Permeability Barriers of Skin and Oral Mucosa.International journal of molecular sciences · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Noriyuki UchidaDepartment of Applied Chemistry, Graduate School of Engineering, Tokyo University of Agriculture and Technology, 2-24-16 Nakacho, Koganei, Tokyo 184-8588, Japan.
Masayoshi YanagiDepartment of Life Science, Faculty of Science, Okayama University of Science, 1-1 Ridai Kita, Okayama 700-0005, Japan.
Hiroki HamadaDepartment of Life Science, Faculty of Science, Okayama University of Science, 1-1 Ridai Kita, Okayama 700-0005, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A transdermal drug delivery system (TDDS) is a method that provides drug adsorption via the skin. TDDS could replace conventional oral administration and blood administration because it is easily accessible. However, it is still difficult to design efficient TDDS due to the high barrier property of skin covered with stratum corneum, which inhibits the permeation of drug molecules. Thus far, TDDS methods by applying physical stimuli such as microneedles and chemical stimuli such as surfactants have been actively developed. However, it has been hard to avoid inflammation at the administration site because these methods partially destroy the skin tissue. On the other hand, TDDS with nanocarriers minimizing damage to the skin tissues has emerged together with the development of nanotechnology in recent years. This review focuses on current trends in TDDS.

Indexed as

microneedlenanocarrierphysical enhancementskintransdermal drug delivery

Identifiers

PMID33525364
PMCPMC7911274

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.