Evidence map›Paper›PMID 33525215›Full record

ArticleActa bio-medica : Atenei Parmensis2020

Antithrombotic prophylaxis in children and adolescents' patients with SARS-CoV-2 (COVID-19) infection: A practical guidance for clinicians.

Mehran Karimi, Haleh Bozorgi, Tahereh Zarei, Mohammadreza Bordbar, Ali Amanati, Arash Safaei, Vincenzo De Sanctis

Open access · greenAbstract read
In one paragraph

Article in Acta bio-medica : Atenei Parmensis, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.3field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Anticoagulant therapy in COVID-19: A narrative review.Clinical and translational science · 2023
    Review
  3. Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Mehran KarimiHematology Research Center, Shiraz University of Medical Sciences, Shiraz . mkarimi820@gmail.com.
Haleh BozorgiHematology Research Center, Shiraz University of Medical Sciences, Shiraz . bozorgihaleh@yahoo.com.
Tahereh ZareiHematology Research Center, Shiraz University of Medical Sciences, Shiraz . taherehzarei71@yahoo.com.
Mohammadreza BordbarHematology Research Center, Shiraz University of Medical Sciences, Shiraz . mbordbar53@gmail.com.
Ali AmanatiProfessor Alborzi Clinical Microbiology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran. dr.amanati14@gmail.com.
Arash SafaeiHematology Research Center, Shiraz University of Medical Sciences, Shiraz . safaeiarash98@gmail.com.
Vincenzo De SanctisCoordinator of the International Network of Clinicians for Endocrinopathies in Thalassemia and Adolescence Medicine (ICET-A), Ferrara, Italy. vdesanctis@libero.it.
Shiraz University of Medical Sciences · IRChild, Adolescent and Family Mental Health · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Severe coronavirus disease 2019 (COVID-19) is often associated with features of hypercoagulable state which can manifest as venous thromboembolism (VTE) and/or microthrombosis. Given the high risk of VTE in critically ill COVID-19 patients, appropriate VTE prophylaxis seems to be an important part of managing these patients. Although many protocols regarding venous thromboembolism (VTE) prophylaxis or therapeutic (full-dose) anticoagulation have been conducted worldwide, primarily in hospitalised adult patients, details on paediatric patients, if included, are limited or incomplete. The current evidences suggest that anticoagulation therapy with low molecular weight heparins (LMWH) appears to be associated with better prognosis in patients with moderate to severe COVID-19 induced coagulopathies or elevated D-dimer levels.  Our recommendations are intended to offer guidance for anticoagulation prophylaxis and treatment in COVID-19 children and adolescent patients and not intend to supersede the clinician judgement. We are also conscious that several clinical questions deserve further studies and clarifications because this area is rapidly evolving.

Indexed as

AdolescentAlgorithmsChildCOVID-19Fibrinolytic AgentsHeparin, Low-Molecular-WeightHumansPractice Guidelines as TopicThrombosisVenous ThromboembolismFibrinolytic AgentsHeparin, Low-Molecular-Weight

Identifiers

PMID33525215
PMCPMC7927562
OpenAlexW3126851834

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.