Evidence map›Paper›PMID 33525077›Full record

ArticleClinical and molecular hepatology2021

Outcomes after liver transplantation in Korea: Incidence and risk factors from Korean transplantation registry.

Jong Man Kim, Deok Gie Kim, Jihyun Kim, Keunsung Lee, Kwang-Woong Lee, Je Ho Ryu, Bong-Wan Kim, Dong Lak Choi, Young Kyoung You, Dong-Sik Kim and 9 more

Open access · goldAbstract read
In one paragraph

Article in Clinical and molecular hepatology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 1 pooled it
12.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 1 synthesis or guideline pooled it, 72 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. ABO-incompatibility and hepatocellular carcinoma recurrence after living donor liver transplantation: stratified by tumor burden.Transplant international : official journal of the European Society for Organ Transplantation · 2026
    Article
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  7. Article
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  9. Observational
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  15. Evidence-based hyponatremia management in liver disease.Clinical and molecular hepatology · 2023
    Review
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 13 institutions in 1 country.

Jong Man KimDepartment of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Deok Gie KimDepartment of Surgery, Yonsei University Wonju College of Medicine, Wonju, Korea.
Jihyun KimNovartis Korea Ltd., Seoul, Korea.
Keunsung LeeNovartis Korea Ltd., Seoul, Korea.
Kwang-Woong LeeDepartment of Surgery, Seoul National University College of Medicine, Seoul, Korea.
Je Ho RyuDivision of Hepato-Biliary-Pancreatic Surgery and liver Transplantation, Department of Surgery, Pusan National University Yangsan Hospital, Pusan National University School of Medicine, Yangsan, Korea.
Bong-Wan KimDepartment of Liver Transplantation and Hepatobiliary Surgery, Ajou University School of Medicine, Suwon, Korea.
Dong Lak ChoiDepartment of Surgery, Catholic University of Daegu College of Medicine, Daegu, Korea.
Young Kyoung YouDepartment of Surgery, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Dong-Sik KimDivision of HBP Surgery & Liver Transplantation, Department of Surgery, Korea University College of Medicine, Seoul, Korea.
Yang Won NahDepartment of Surgery, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, Korea.
Koo Jeong KangDepartment of Surgery, Dongsan Medical Center, Keimyung University School of Medicine, Daegu, Korea.
Jai Young ChoDepartment of Surgery, Mokdong Hospital, Ewha Womans University School of Medicine, Seoul, Korea.
Geun HongDepartment of Surgery, Mokdong Hospital, Ewha Womans University School of Medicine, Seoul, Korea.
Hee Chul YuDepartment of Surgery, Jeonbuk National University Medical School, Jeonju, Korea.
Ju Ik MoonDepartment of Surgery, Konyang University Hospital, Konyang University College of Medicine, Daejeon, Korea.
Dongho ChoiDepartment of Surgery, Hanyang University College of Medicine, Seoul, Korea.
Shin HwangDepartment of Surgery, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Korea.
Myoung Soo KimDepartment of Surgery, Yonsei University College of Medicine, Seoul, Korea.
Novartis (South Korea) · KRYonsei University · KRCatholic University of Daegu · KREwha Womans University · KRAjou University · KRAsan Medical Center · KRCatholic University of Korea · KRJeonbuk National University · KRKeimyung University · KRKonyang University Hospital · KRPusan National University Yangsan Hospital · KRSamsung Medical Center · KRUniversity of Ulsan · KR

Funding

Korea Centers for Disease Control and Prevention 2014-ER6301-00Korea Centers for Disease Control and Prevention 2014-ER6301-01Korea Centers for Disease Control and Prevention 2014-ER6301-02Korea Centers for Disease Control and Prevention 2017-ER6301-00Korea Centers for Disease Control and Prevention 2017-ER6301-01Korea Centers for Disease Control and Prevention 2017-ER6301-02Novartis Korea Ltd
6 · The paper itself

Abstract

BACKGROUND/

aimsTo analyze the incidence and risk factors of outcomes after liver transplantation (LT) in the Korean population.

methodsThis study analyzed data from the liver cohort of Korean Organ Transplantation Registry (KOTRY) who had LT between May 2014 and December 2017. Study measures included the incidence of post-LT outcomes in recipients of living donor LT (LDLT) and deceased donor LT (DDLT). Cox multivariate proportional hazards model was used to determine the potential risk factors predicting the outcomes.

resultsA total of 2,563 adult recipients with LT (LDLT, n=1,956; DDLT, n=607) were included, with mean±standard deviation age of 53.9±8.9 years, and 72.2% were male. The post-LT outcomes observed in each LDLT and DDLT recipients were death (4.0% and 14.7%), graft loss (5.0% and 16.1%), rejection (7.0% and 12.0%), renal failure (2.7% and 13.8%), new onset of diabetes (12.5% and 15.4%), and hepatocellular carcinoma (HCC) recurrence (both 6.7%). In both LDLT and DDLT recipients, the most common post-LT complications were renal dysfunction (33.6% and 51.4%), infection (26.7% and 48.4%), and surgical complication (22.5% and 23.9%). Incidence of these outcomes were generally higher among recipients of DDLT than LDLT. Multivariate analysis indicated recipient age and DDLT as significant risk factors associated with death and graft loss. DDLT and ABO incompatible transplant were prognostic factors for rejection, and HCC beyond Milan criteria at pre-transplant was a strong predictor of HCC recurrence.

conclusionThis study is a good indicator of the post-LT prognosis in the Korean population and suggests a significant burden of post-LT complications.

Indexed as

Liver TransplantationAdultCarcinoma, HepatocellularEnd Stage Liver DiseaseFemaleHumansIncidenceLiver NeoplasmsLiving DonorsMaleMiddle AgedNeoplasm Recurrence, LocalRegistriesRepublic of KoreaRetrospective StudiesRisk FactorsIncidenceLiver transplantationRenal insufficiencyRisk factors

Identifiers

PMID33525077
PMCPMC8273644
OpenAlexW3128728168

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.