Evidence map›Paper›PMID 33524795›Full record

ArticleCell calcium2021

The role of potassium and host calcium signaling in Toxoplasma gondii egress.

Stephen A Vella, Christina A Moore, Zhu-Hong Li, Miryam A Hortua Triana, Evgeniy Potapenko, Silvia N J Moreno

Open access · greenAbstract read
In one paragraph

Article in Cell calcium, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
4.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 36 citations in OpenAlex.

  1. Article
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  8. Orthologs ofMicrobiology spectrum · 2024
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  9. Changes in KInternational journal of molecular sciences · 2023
    Review
  10. Animal venoms: a novel source of anti-Frontiers in pharmacology · 2023
    Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. eLife · 2021
    Article
  16. Article
  17. Calcium signaling in intracellular protist parasites.Current opinion in microbiology · 2021
    Review
  18. Article
  19. CaMolecular microbiology · 2021
    Article
  20. Ferlins and TgDOC2 inLife (Basel, Switzerland) · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Stephen A VellaCenter for Tropical and Emerging Global Diseases, University of Georgia, United States; Department of Microbiology, University of Georgia, United States.
Christina A MooreCenter for Tropical and Emerging Global Diseases, University of Georgia, United States; Department of Cellular Biology, University of Georgia, Athens, GA, 30602, United States.
Zhu-Hong LiCenter for Tropical and Emerging Global Diseases, University of Georgia, United States.
Miryam A Hortua TrianaCenter for Tropical and Emerging Global Diseases, University of Georgia, United States.
Evgeniy PotapenkoCenter for Tropical and Emerging Global Diseases, University of Georgia, United States.
Silvia N J MorenoCenter for Tropical and Emerging Global Diseases, University of Georgia, United States; Department of Cellular Biology, University of Georgia, Athens, GA, 30602, United States. Electronic address: smoreno@uga.edu.
University of Georgia · US

Funding

Training in Tropical and Emerging Global Diseases - SupplementT32AI060546 · NIAID · UNIVERSITY OF GEORGIA (UGA) · PI Silvia N Moreno, Vasant Muralidharan · 2004 to 2026
$5.1M
The Toxoplasma apicoplast and calcium signalingR01AI128356 · NIAID · UNIVERSITY OF GEORGIA · PI MORENO, SILVIA N · 2017 to 2021
$2.0M
NIAID NIH HHS R01 AI128356NIAID NIH HHS T32 AI060546
6 · The paper itself

Abstract

Toxoplasma gondii is an obligate intracellular parasite and replicates inside a parasitophorous vacuole (PV) within the host cell. The membrane of the PV (PVM) contains pores that permits for equilibration of ions and small molecules between the host cytosol and the PV lumen. Ca

Indexed as

Calcium SignalingHost-Pathogen InteractionsAnimalsCalciumCell MembraneCytosolHeLa CellsHumansIntracellular SpaceModels, BiologicalParasitesPotassiumToxoplasmaCalciumPotassiumCalcium signalingGCaMP6fGeneticallyEncoded Calcium IndicatorsR-GECOToxoplasma egressToxoplasma gondii

Identifiers

PMID33524795
PMCPMC7914212
OpenAlexW3122821072

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.