Evidence map›Paper›PMID 33524450›Full record

ArticleAmerican journal of infection control2021

New technique to evaluate decontamination methods for filtering facepiece respirators.

Evanly Vo, Samy Rengasamy, Susan Xu, Matthew Horvatin, Ziqing Zhuang

Open access · greenAbstract read
In one paragraph

Article in American journal of infection control, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Evanly VoNational Institute for Occupational Safety and Health, National Personal Protective Technology Laboratory, Pittsburgh, PA. Electronic address: eav8@cdc.gov.
Samy RengasamyNational Institute for Occupational Safety and Health, National Personal Protective Technology Laboratory, Pittsburgh, PA.
Susan XuNational Institute for Occupational Safety and Health, National Personal Protective Technology Laboratory, Pittsburgh, PA.
Matthew HorvatinAmentum, Aiken, SC.
Ziqing ZhuangNational Institute for Occupational Safety and Health, National Personal Protective Technology Laboratory, Pittsburgh, PA.
National Institute for Occupational Safety and Health · US

Funding

Intramural CDC HHS CC999999
6 · The paper itself

Abstract

backgroundA major concern among health care experts is a shortage of N95 filtering facepiece respirators (FFRs) during a pandemic. One option for mitigating an FFR shortage is to decontaminate and reuse the devices. The focus of this study was to develop a new evaluation technique based on 3 major decontamination requirements: (1) inactivating viruses, (2) not altering the respirator properties, and (3) not leaving any toxic byproduct on the FFR.

methodsHydrophilic and hydrophobic FFRs were contaminated with MS2 virus. In the solution-based deposition, the virus-containing liquid droplets were spiked directly onto FFRs, while in the vapor-based and aerosol-based depositions, the viral particles were loaded onto FFRs using a bio-aerosol testing system. Ultraviolet germicidal irradiation (UVGI) and moist heat (MH) decontamination methods were used for inactivation of viruses applied to FFRs.

resultsBoth UVGI and MH methods inactivated viruses (>5-log reduction of MS2 virus; in 92% of both method experiments, the virus was reduced to levels below the detection limit), did not alter the respirator properties, and did not leave any toxic byproduct on the FFRs.

conclusionsBoth UVGI and MH methods could be considered as promising decontamination candidates for inactivation of viruses for respirator reuse during shortages.

Indexed as

Equipment ReuseRespiratory Protective DevicesDecontaminationHumansPandemicsUltraviolet RaysVentilators, MechanicalDisinfectionInfection controlMoist heatMS2 virusN95 respiratorUVGI

Identifiers

PMID33524450
PMCPMC9494706
OpenAlexW3128062200

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.