ArticlePloS one2021
Femoral neck strain prediction during level walking using a combined musculoskeletal and finite element model approach.
Article in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.
- Multibody dynamics-based musculoskeletal modeling for gait analysis: a systematic review.Journal of neuroengineering and rehabilitation · 2024Pooled it
- Multi-scale modelling of mouse tibia loading reveals the critical role of muscle insertion surfaces.Biomechanics and modeling in mechanobiology · 2026Article
- Dataset for rapid estimation of femoral neck loading during gait and dynamic exercises.Scientific data · 2026Article
- In silico analysis of fixation device strain patterns in the postoperative proximal femur: Effects of bone quality during gait.Clinical biomechanics (Bristol, Avon) · 2025Article
- The central collinear start point in femoral reconstruction nailing decreases ultimate failure load of the femoral neck: a cadaveric biomechanics study.OTA international : the open access journal of orthopaedic trauma · 2025Article
- Gait function progress in a patient with a femoral neck fracture who underwent rehabilitation during prolonged surgical waiting time: a case study.Journal of physical therapy science · 2025Article
- Understanding Hip Contact Stress Based on Types of Physical Activity: A Systematic Review.Health science reports · 2025Review
- Analysis of Muscle Forces and Their Impact on Femoral Bone Stresses Using Response Surface Methodology (RSM).Biomedical engineering and computational biology · 2025Article
- Lower limb joint loading during high-impact activities: implication for bone health.JBMR plus · 2024Article
- Automatic segmentation of lower limb muscles from MR images of post-menopausal women based on deep learning and data augmentation.PloS one · 2024Article
- Effect of Muscle Forces on Femur During Level Walking Using a Virtual Population of Older Women.Methods in molecular biology (Clifton, N.J.) · 2024Article
- Automatic segmentation of skeletal muscles from MR images using modified U-Net and a novel data augmentation approach.Frontiers in bioengineering and biotechnology · 2024Article
- Improving the Hip Fracture Risk Prediction with a Statistical Shape-and-Intensity Model of the Proximal Femur.Annals of biomedical engineering · 2022Article
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 2 countries.
Funding
Abstract
Recently, coupled musculoskeletal-finite element modelling approaches have emerged as a way to investigate femoral neck loading during various daily activities. Combining personalised gait data with finite element models will not only allow us to study changes in motion/movement, but also their effects on critical internal structures, such as the femur. However, previous studies have been hampered by the small sample size and the lack of fully personalised data in order to construct the coupled model. Therefore, the aim of this study was to build a pipeline for a fully personalised multiscale (body-organ level) model to investigate the strain levels at the femoral neck during a normal gait cycle. Five postmenopausal women were included in this study. The CT and MRI scans of the lower limb, and gait data were collected for all participants. Muscle forces derived from the body level musculoskeletal models were used as boundary constraints on the finite element femur models. Principal strains were estimated at the femoral neck region during a full gait cycle. Considerable variation was found in the predicted peak strain among individuals with mean peak first principal strain of 0.24% ± 0.11% and mean third principal strain of -0.29% ± 0.24%. For four individuals, two overall peaks of the maximum strains were found to occur when both feet were in contact with the floor, while one individual had one peak at the toe-off phase. Both the joint contact forces and the muscular forces were found to substantially influence the loading at the femoral neck. A higher correlation was found between the predicted peak strains and the gluteus medius (R2 ranged between 0.95 and 0.99) than the hip joint contact forces (R2 ranged between 0.63 and 0.96). Therefore, the current findings suggest that personal variations are substantial, and hence it is important to consider multiple subjects before deriving general conclusions for a target population.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.