Evidence map›Paper›PMID 33523953›Full record

ArticleScience advances2021

Wearable plasmonic-metasurface sensor for noninvasive and universal molecular fingerprint detection on biointerfaces.

Yingli Wang, Chen Zhao, Jingjing Wang, Xuan Luo, Lijuan Xie, Shijie Zhan, Jongmin Kim, Xiaozhi Wang, Xiangjiang Liu, Yibin Ying

Abstract read
In one paragraph

Article in Science advances, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 78 papers.

0numbers the graph read from it
0cells of the map it votes in
78citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

78 citing papers in PubMed.

  1. Wafer-scale conformal metasurface optics.Nature communications · 2026
    Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Dynamic Optical Lattices Through Conducting Polymer-Gated Confinement.Advanced materials (Deerfield Beach, Fla.) · 2026
    Article
  10. Review
  11. Review
  12. Review
  13. Unperceivable Designs of Wearable Electronics.Advanced materials (Deerfield Beach, Fla.) · 2025
    Review
  14. Review
  15. Photonic Nanomaterials for Wearable Health Solutions.Advanced materials (Deerfield Beach, Fla.) · 2025
    Review
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article

18 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yingli WangCollege of Biosystems Engineering and Food Science, Zhejiang University, Hangzhou 310058, China.ORCID 0000-0001-8747-6068
Chen ZhaoCollege of Biosystems Engineering and Food Science, Zhejiang University, Hangzhou 310058, China.ORCID 0000-0002-7614-0662
Jingjing WangCollege of Biosystems Engineering and Food Science, Zhejiang University, Hangzhou 310058, China.
Xuan LuoCollege of Biosystems Engineering and Food Science, Zhejiang University, Hangzhou 310058, China.
Lijuan XieCollege of Biosystems Engineering and Food Science, Zhejiang University, Hangzhou 310058, China.ORCID 0000-0002-1008-5410
Shijie ZhanDepartment of Engineering, University of Cambridge, Cambridge CB3 0FF, UK.
Jongmin KimDepartment of Engineering, University of Cambridge, Cambridge CB3 0FF, UK.
Xiaozhi WangCollege of Information Science and Electronic Engineering, Zhejiang University, Hangzhou 310058, China.ORCID 0000-0002-4290-9023
Xiangjiang LiuCollege of Biosystems Engineering and Food Science, Zhejiang University, Hangzhou 310058, China. xjliu@zju.edu.cn.ORCID 0000-0002-5419-669X
Yibin YingCollege of Biosystems Engineering and Food Science, Zhejiang University, Hangzhou 310058, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Wearable sensing technology is an essential link to future personalized medicine. However, to obtain a complete picture of human health, it is necessary but challenging to track multiple analytes inside the body simultaneously. Here, we present a wearable plasmonic-electronic sensor with "universal" molecular recognition ability. Flexible plasmonic metasurface with surface-enhanced Raman scattering (SERS)-activity is introduced as the fundamental sensing component in a wearable sensor since we solved the technical challenge of maintaining the plasmonic activities of their brittle nanostructures under various deformations. Together with a flexible electronic sweat extraction system, our sensor can noninvasively extract and "fingerprint" analytes inside the body based on their unique SERS spectra. As a proof-of-concept example, we successfully monitored the variation of trace-amounts drugs inside the body and obtained an individual's drug metabolic profile. Our sensor bridges the existing gap in wearable sensing technology by providing a universal, sensitive molecular tracking means to assess human health.

Identifiers

PMID33523953
PMCPMC10964967

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.