ArticleScience advances2021
Highly sensitive VOC detectors using insect olfactory receptors reconstituted into lipid bilayers.
Article in Science advances, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 83 citations in OpenAlex.
- Ectopic Olfactory Receptors in Oral Health and Disease: Molecular Links Between Chemosensing, Tissue Repair, Inflammation, and Cancer.International journal of molecular sciences · 2026Review
- Operational mechanisms and application advances in artificial olfactory systems.Biomedical engineering online · 2026Review
- Shape-Encoded Hydrogel Sensor Particles Enable Multiplex Odorant Detection Through Deep-learning Classification.Small (Weinheim an der Bergstrasse, Germany) · 2025Article
- Bio-Inspired Neuromorphic Sensory Systems from Intelligent Perception to Nervetronics.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Review
- Biohybrid living robotics: A comprehensive review of recent advances, technological innovation, and future prospects.npj Robotics · 2025Article
- A Drosophila-inspired intelligent olfactory biomimetic sensing system for gas recognition in complex environments.Microsystems & nanoengineering · 2024Article
- High-throughput ligand profile characterization in novel cell lines expressing seven heterologous insect olfactory receptors for the detection of volatile plant biomarkers.Scientific reports · 2023Article
- Biosensors for Odor Detection: A Review.Biosensors · 2023Review
- Activity of Single Insect Olfactory Receptors Triggered by Airborne Compounds Recorded in Self-Assembled Tethered Lipid Bilayer Nanoarchitectures.ACS applied materials & interfaces · 2023Article
- Selection Behavior and OBP-Transcription Response of Western Flower Thrips,International journal of molecular sciences · 2023Article
- Function Investigations and Applications of Membrane Proteins on Artificial Lipid Membranes.International journal of molecular sciences · 2023Review
- Applying genetic technologies to combat infectious diseases in aquaculture.Reviews in aquaculture · 2023Review
- Artificial Olfactory Biohybrid System: An Evolving Sense of Smell.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023Review
- Progress in the Development of Detection Strategies Based on Olfactory and Gustatory Biomimetic Biosensors.Biosensors · 2022Review
- Review
- Anhydrobiotic chironomid larval motion-based multi-sensing microdevice for the exploration of survivable locations.iScience · 2022Article
- Biting Innovations of Mosquito-Based Biomaterials and Medical Devices.Materials (Basel, Switzerland) · 2022Review
- Variation in volatile organic compounds in Atlantic salmon mucus is associated with resistance to salmon lice infection.Scientific reports · 2022Article
- Highly sensitive and fast-response ethanol sensing of porous CoRSC advances · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This paper reports a volatile organic compound (VOC) sensor based on olfactory receptors that were reconstituted into a lipid bilayer and used in a specifically designed gas flow system for rapid parts per billion (ppb)-level detection. This VOC sensor achieves both rapid detection and high detection probability because of its gas flow system and array design. Specifically, the gas flow system includes microchannels and hydrophobic microslits, which facilitate both the introduction of gas into the droplet and droplet mixing. We installed this system into a parallel lipid bilayer device and subsequently demonstrated parts per billion-level (0.5 ppb) detection of 1-octen-3-ol in human breath. Therefore, this system extends the various applications of biological odorant sensing, including breath diagnosis systems and environmental monitoring.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.