Evidence map›Paper›PMID 33523392›Full record

ArticleLasers in medical science2022

Monitoring of the choline/lipid ratio by

Erfan Saatchian, Sina Ehsani, Abolfazl Sarikhani, Habib Ghaznavi, Alireza Montazerabadi, Ali Shakeri-Zadeh

Abstract read
PubMed Publisher
In one paragraph

Article in Lasers in medical science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Erfan SaatchianMedical Physics Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Sina EhsaniMedical Physics Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Abolfazl SarikhaniFinetech in Medicine Research Center, Iran University of Medical Science, Tehran, Iran.
Habib GhaznaviPharmacology Research Center, Zahedan University of Medical Sciences (ZaUMS), Zahedan, Iran. dr.ghaznavi@zaums.ac.ir.ORCID http://orcid.org/0000-0002-4629-1697
Alireza MontazerabadiMedical Physics Research Center, Mashhad University of Medical Sciences, Mashhad, Iran. alireza.montazerabadi@gmail.com.
Ali Shakeri-ZadehFinetech in Medicine Research Center, Iran University of Medical Science, Tehran, Iran.
Mashhad University of Medical Sciences · IRIran University of Medical Sciences · IRZahedan University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nanotechnology-based photothermal therapy (NPTT) is a new emerging modality of cancer therapy. To have the right prediction and early detection of response to NPTT, it is necessary to get rapid feedback from a tumor treated by NPTT procedure and stay informed of what happens in the tumor site. We performed this study to find if proton magnetic resonance spectroscopy (1H-MRS) can be well responsive to such an imperative requirement. We considered various treatment groups including gold nanoparticles (AuNPs), laser, and the combination of AuNPs and laser (NPTT group). Therapeutic effects on CT26 colon tumor-bearing BALB/c mice were studied by looking at alterations that happened in 1H-MRS signals and tumor size after conducting treatment procedures. In MRS studies, the alterations of choline and lipid concentrations and their ratio were investigated. Having normalized the metabolite peak to water peak, we found a significant decrease in choline concentration post-NPTT (from (1.25 ± 0.05) × 10

Indexed as

Metal NanoparticlesNeoplasmsAnimalsCholineGoldLipidsMiceProton Magnetic Resonance SpectroscopyCholineGoldLipidsCancerCholine/lipid ratioNano-photo-thermal therapyProton MR spectroscopyTherapeutic response

Identifiers

PMID33523392
OpenAlexW3128729952

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.